A comprehensive review on pilot plant scale up and platform technology

The pharmaceutical business uses pilot plant scale-up strategies to create reliable manufacturing procedures and turn lab-scale formulas into commercial products. The place called Pilot is where the five elements Material, Man, Method, and Machine are combined to manufacture things. A tiny, basic lab scale formula will be tested on a replica of the intended plant in the pilot plant before spending a significant amount of money on a production unit. Scaling up a pilot plant provides information on formula examination, reviewing the range of pertinent processing equipment, understanding raw material specifications, production rate, and physical space requirements. It can hold accurate documentation and reports for analysis in support of the GMP procedure. This review research discusses the factors for solids, liquids, and semisolids for scaling up pilot plants. The primary goal of a pilot plant is to "identify errors on a small scale and generate revenue on a large scale."