[颈内动脉病理性迂曲患者手术治疗的有效性和安全性]。

Q4 Medicine
A V Gavrilenko, A V Abramyan, V A Kochetkov, E A Tarabrin
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引用次数: 0

摘要

迄今为止,全世界尚未就PI BSA患者的手术适应症、手术类型及其与保守治疗的比较进行过多中心随机临床试验:研究的目的是改善颈内动脉病理性迂曲患者的手术治疗效果:研究纳入了119例PI ICA患者(男性41例(34%),女性78例(66%)),年龄在34岁至71岁之间(平均年龄为53.2±7.5岁),分为两组。第一组的 64 名患者(54%)接受了下口 BSA 切除术,第二组的 55 名患者(46%)接受了 BSA 修复术。根据神经系统疾病的程度,患者按照 A.V. Pokrovsky 的分类进行分配:术后早期,1 名患者出现了 TIA,5 名患者出现了短暂的颅神经损伤。在 5 年的随访中,没有一名患者出现 TIA、IS 或其他血管事件。在手术早期,两组患者的疗效没有明显差异。在长期随访期间(术后 5 年),I 组患者出现无症状的频率较高:结论:切除并置换病态迂曲的颈内动脉(ICA)是一种安全有效的手术治疗方法。应进行多中心随机试验,比较手术治疗 PI ICA 和保守治疗的效果,以有效治疗患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Efficacy and safety of surgical treatment of patients with pathological tortuosity of the internal carotid artery].

No multicenter randomized clinical trial has been conducted worldwide to date on indications, types of surgery and their comparison with conservative treatment in patients with PI BSA.

Objective: Of the study is to improve the results of surgical treatment in patients with pathological tortuosity of the internal carotid artery.

Material and methods: The study included 119 patients (41 (34%) men and 78 (66%) women) with PI ICA aged 34 to 71 years (average age 53.2±7.5 years) divided into 2 groups. 64 patients (54%) of group I underwent BSA resection with lower mouth and 55 patients (46%) of group II underwent BSA prosthetics. Depending on the degree of neurological disorders, patients were distributed according to the classification of A.V. Pokrovsky.

Results: In the early postoperative period, TIA was noted in one patient, and transient lesions of the cranial nerves were observed in 5 patients. During 5 years of follow-up, none of the patients developed TIA, IS or other vascular events. In the early surgical period, there were no significant differences in effectiveness between the groups of patients. In the long-term period (5 years after surgery), a higher frequency of asymptomatic patients was noted in group I.

Conclusion: Resection and replacement of a pathologically tortuous internal carotid artery (ICA) is a safe and effective surgical treatment. A multicenter randomized trial should be conducted to compare the effectiveness of surgical treatment of PI ICA with a conservative approach to effectively treat patients.

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来源期刊
Khirurgiya
Khirurgiya Medicine-Medicine (all)
CiteScore
0.70
自引率
0.00%
发文量
161
期刊介绍: Хирургия отдельных областей сердце, сосуды легкие пищевод молочная железа желудок и двенадцатиперстная кишка кишечник желчевыводящие пути печень
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