Mahmud Omar, Mohammad Omar, Saleh Nassar, Adi Lahat, Kassem Sharif
{"title":"乳糜泻与 2 型炎症性疾病之间的遗传关联:孟德尔随机分析","authors":"Mahmud Omar, Mohammad Omar, Saleh Nassar, Adi Lahat, Kassem Sharif","doi":"10.1101/2024.01.18.24301488","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Epidemiological data suggest an association with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis, however, genetic associations remain unclear, prompting this study to explore their potential genetic interplay.","PeriodicalId":501258,"journal":{"name":"medRxiv - Gastroenterology","volume":"56 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Genetic Associations Between Celiac Disease and Type 2 Inflammatory Diseases: A Mendelian Randomization Analysis\",\"authors\":\"Mahmud Omar, Mohammad Omar, Saleh Nassar, Adi Lahat, Kassem Sharif\",\"doi\":\"10.1101/2024.01.18.24301488\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<strong>Background</strong> Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Epidemiological data suggest an association with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis, however, genetic associations remain unclear, prompting this study to explore their potential genetic interplay.\",\"PeriodicalId\":501258,\"journal\":{\"name\":\"medRxiv - Gastroenterology\",\"volume\":\"56 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Gastroenterology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.01.18.24301488\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.01.18.24301488","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Genetic Associations Between Celiac Disease and Type 2 Inflammatory Diseases: A Mendelian Randomization Analysis
Background Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Epidemiological data suggest an association with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis, however, genetic associations remain unclear, prompting this study to explore their potential genetic interplay.