乳糜泻与 2 型炎症性疾病之间的遗传关联:孟德尔随机分析

Mahmud Omar, Mohammad Omar, Saleh Nassar, Adi Lahat, Kassem Sharif
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引用次数: 0

摘要

背景 乳糜泻是一种由麸质引发的自身免疫性疾病,以其全身性炎症效应而闻名。流行病学数据表明,乳糜泻与哮喘、过敏性鼻炎和特应性皮炎等 2 型炎症性疾病有关联,但遗传关联仍不明确,这促使本研究探索其潜在的遗传相互作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Genetic Associations Between Celiac Disease and Type 2 Inflammatory Diseases: A Mendelian Randomization Analysis
Background Celiac disease, a gluten-triggered autoimmune disorder, is known for its systemic inflammatory effects. Epidemiological data suggest an association with type 2 inflammatory diseases like asthma, allergic rhinitis, and atopic dermatitis, however, genetic associations remain unclear, prompting this study to explore their potential genetic interplay.
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