Mary Catherine C Minnig, Yvonne M Golightly, Amanda E Nelson
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引用次数: 0
摘要
综述目的:这篇综述重点介绍了最近发表的有关骨关节炎(OA)流行病学的研究,包括与研究不足的人群和关节、成像以及人工智能(AI)方法的进展有关的主题:当代研究提高了我们对通常研究不足地区的 OA 负担的认识,包括高收入国家、中东和北非(MENA)及拉丁美洲的少数族裔和种族。此外,研究人员还努力探索手部、足部和踝关节等以前未被充分研究的关节的 OA 负担和风险因素。OA 成像技术的进步与旨在预测疾病表型、进展和结果的人工智能方法的发展同步进行。总结:继续努力扩大我们对未充分研究人群 OA 的了解,将有助于制定有针对性的具体干预措施,并为旨在减少这些群体疾病负担的政策变化提供信息。在未充分研究的关节中,与 OA 相关的负担和残疾非常显著,因此需要进一步开展研究工作,从而找到有效的治疗方案。人工智能方法在预测 OA 表型和进展方面取得了可喜的成果,这也可能鼓励开发有针对性的改变 OA 疾病的药物(DMOADs)。
Epidemiology of osteoarthritis: literature update 2022-2023.
Purpose of review: This review highlights recently published studies on osteoarthritis (OA) epidemiology, including topics related to understudied populations and joints, imaging, and advancements in artificial intelligence (AI) methods.
Recent findings: Contemporary research has improved our understanding of the burden of OA in typically understudied regions, including ethnic and racial minorities in high-income countries, the Middle East and North Africa (MENA) and Latin America. Efforts have also been made to explore the burden and risk factors in OA in previously understudied joints, such as the hand, foot, and ankle. Advancements in OA imaging techniques have occurred alongside the developments of AI methods aiming to predict disease phenotypes, progression, and outcomes.
Summary: Continuing efforts to expand our knowledge around OA in understudied populations will allow for the creation of targeted and specific interventions and inform policy changes aimed at reducing disease burden in these groups. The burden and disability associated with OA is notable in understudied joints, warranting further research efforts that may lead to effective therapeutic options. AI methods show promising results of predicting OA phenotypes and progression, which also may encourage the creation of targeted disease modifying OA drugs (DMOADs).
期刊介绍:
A high impact review journal which boasts an international readership, Current Opinion in Rheumatology offers a broad-based perspective on the most recent and exciting developments within the field of rheumatology. Published bimonthly, each issue features insightful editorials and high quality invited reviews covering two or three key disciplines which include vasculitis syndromes, medical physiology and rheumatic diseases, crystal deposition diseases and rheumatoid arthritis. Each discipline introduces world renowned guest editors to ensure the journal is at the forefront of knowledge development and delivers balanced, expert assessments of advances from the previous year.