微流中细菌聚集的动态变化

Ana Carpio, Baldvin Einarsson, David R. Espeso
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引用次数: 0

摘要

生物膜是生长在潮湿表面的细菌聚集体。在导管壁上自然形成的薄而均匀的生物膜可作为生物传感器,在不破坏微系统(MEMS)的情况下提供有关微系统状态的信息。然而,不受控制的生物膜生长可能会在很大程度上扰乱其生长环境,增加阻力并堵塞管道。为了确保生物膜的扩张受到控制,我们需要了解外部变量对其结构的影响。我们建立了一个混合模型,用于对层流微流中生长的生物膜进行计算研究。生物质根据粘附、侵蚀和运动的随机规则发生演变,每个阶段的流场都有数值近似值。该模型通过研究三维角流中流线的形成进行了测试,从而深入了解了外部变量对流线结构的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dynamics of bacterial aggregates in microflows
Biofilms are bacterial aggregates that grow on moist surfaces. Thin homogeneous biofilms naturally formed on the walls of conducts may serve as biosensors, providing information on the status of microsystems (MEMS) without disrupting them. However, uncontrolled biofilm growth may largely disturb the environment they develop in, increasing the drag and clogging the tubes. To ensure controlled biofilm expansion we need to understand the effect of external variables on their structure. We formulate a hybrid model for the computational study of biofilms growing in laminar microflows. Biomass evolves according to stochastic rules for adhesion, erosion and motion, informed by numerical approximations of the flow fields at each stage. The model is tested studying the formation of streamers in three dimensional corner flows, gaining some insight on the effect of external variables on their structure.
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