PKA 如何帮助心肌细胞驾驭慢性压力

IF 3.3 2区医学 Q1 PHYSIOLOGY

Journal of General Physiology Pub Date : 2024-02-05 Epub Date: 2024-01-16 DOI:10.1085/jgp.202313534

Ben Short

引用次数: 0

摘要

JGP研究（Bernas等人，2024年。J. Gen. Physiol.https://doi.org/10.1085/jgp.202313436）表明，通过改变微管动力学，PKA的持续激活促进了Nav1.5通道向椎间盘的输送。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

How PKA helps cardiomyocytes Navigate chronic stress.

JGP study (Bernas et al. 2024. J. Gen. Physiol.https://doi.org/10.1085/jgp.202313436) suggests that, by altering microtubule dynamics, persistent PKA activation promotes the delivery of Nav1.5 channels to intercalated discs.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of General Physiology 医学-生理学

CiteScore

6.00

自引率

10.50%

发文量

审稿时长

6-12 weeks

期刊介绍： General physiology is the study of biological mechanisms through analytical investigations, which decipher the molecular and cellular mechanisms underlying biological function at all levels of organization. The mission of Journal of General Physiology (JGP) is to publish mechanistic and quantitative molecular and cellular physiology of the highest quality, to provide a best-in-class author experience, and to nurture future generations of independent researchers. The major emphasis is on physiological problems at the cellular and molecular level.