抗IL-6受体抗体治疗期间腹膜后泛起的赤痢链球菌亚种引起的链球菌中毒性休克综合征:病例报告。

IF 0.9 Q4 RHEUMATOLOGY
Sho Fujimoto, Yoshihiro Eriguchi, Rinto Nakamura, Sota Kamikawa, Akiko Yonekawa, Noriko Miyake, Nobuyuki Ono, Hiroaki Niiro
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引用次数: 0

摘要

一名患有成人型斯蒂尔病的 53 岁男子在腹膜后泛起炎症后,因痢疾链球菌马氏亚种(SDSE)而患上了严重的链球菌中毒性休克综合征(STSS)。他正在接受白细胞介素-6受体抑制剂托西珠单抗(TCZ)治疗。TCZ对SDSE感染的免疫反应和病理生理学的调节作用可能导致腹膜后泛发性炎和非典型STSS,并伴有延迟性休克和软组织炎症爆发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Streptococcal toxic shock syndrome due to Streptococcus dysgalactiae subsp. equisimilis from retroperitoneal panniculitis during the treatment with anti-IL-6 receptor antibody: A case report.

A 53-year-old man with adult-onset Still's disease developed severe streptococcal toxic shock syndrome (STSS) due to Streptococcus dysgalactiae subsp. equisimilis (SDSE), following retroperitoneal panniculitis. He was receiving tocilizumab (TCZ), an interleukin-6 receptor inhibitor. The modifying effect of TCZ on the immune response and the pathophysiology of SDSE infection may have led to retroperitoneal panniculitis and atypical STSS with delayed shock and flare of soft tissue inflammation.

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