受牙龈炎影响的早产孕妇血清中白细胞介素-6(IL-6)和白细胞介素-8(IL-8)水平的变化

Shaden Husham, Ghada Taha
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引用次数: 0

摘要

背景:牙周病会增加孕妇的局部和全身炎症反应,从而可能导致早产:牙周病会增加孕妇局部和全身的炎症反应,从而可能导致早产:检测患有牙龈炎的孕妇血清中促炎性细胞因子(白细胞介素-6、白细胞介素-8)水平与早产的关系:在这项病例对照研究中,共有 85 名孕妇参与研究,其中 55 人患有牙龈炎:25 人早产,30 人足月分娩。对照组中有 30 名牙龈健康的孕妇。她们都是在 2022 年 11 月至 2023 年 5 月期间从 Al-Ramadi 妇科和儿科教学医院挑选出来的。研究人员采集了所有参与者的血液样本,并通过免疫吸附测定()试剂盒检测了生物标志物细胞因子:本次研究显示,与对照组相比,早产牙龈炎组和足月分娩孕妇牙龈炎组的白细胞介素-6和白细胞介素-8水平升高,差异有统计学意义( ):结论:白细胞介素-6和白细胞介素-8水平最高的牙龈炎孕妇比白细胞介素-6和白细胞介素-8水平较低的孕妇和无牙龈炎的孕妇更容易早产:接受:2023年6月收稿日期:2023年6月接受日期:2023年8月发表日期:2024年1月Jan.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes in levels of Interleukin-6 (IL-6) and Interleukin-8 (IL-8) in the Serum of Preterm Delivery Pregnant Women Affected by Gingivitis
Background: Periodontal disease increases local and systemic inflammatory responses in pregnant women, which may lead to premature delivery. Objectives: To detect maternal serum levels of proinflammatory cytokine (Interleukine-6, Interleukin-8) with preterm delivery in pregnant women suffering from gingivitis. Cases and methods: In this case-control study, a total of 85 pregnant women, were included in the study, of whom 55 had gingivitis: 25 preterm deliveries and 30 full-term deliveries. Thirty healthy pregnant women with healthy gingiva were in the control group. They were selected from Al-Ramadi Teaching Hospital for Gynecology and Pediatrics, from November 2022 to May 2023. Blood samples were collected from all participants and the biomarkers cytokines were detected by immunosorbent assay ( ) kits. Results: The current study showed an increased level of interleukin-6 and interleukin-8 in the pre-term delivery gingivitis group followed by full-term-delivery pregnant groups having gingivitis compared with the control group, with statistically highly significant differences ( ). Conclusion: Pregnant women with gingivitis with the highest levels of Interlukine-6 and Interlukine-8 were more prone to have premature delivery than those with lower levels of Interleukins and those without gingivitis. Received: June, 2023 Accepted: Aug, 2023 Published: Jan..2024  
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