单吻合胃旁路手术:对糖尿病参数的影响

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Arya Singh, Rahnuma Ahmad, Susmita Sinha, Md. Ahsanul Haq, M. Narwaria, Ankur Sharma, Mainul Haque, Santosh Kumar, Nandita Sanghani
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引用次数: 0

摘要

导言:体重增加过多会导致各种代谢紊乱,如糖尿病,并进一步增加体重指数(BMI)。因此,患者会进入一个恶性循环,导致不可逆转的健康损害。减肥手术在减轻体重、使体重指数恢复正常方面取得了积极成果,可将血糖水平降至接近正常。糖尿病的缓解可归因于炎症的减轻、胰岛素抵抗的改善、YY 肽的降低以及身体代谢状态的整体改善。研究方法随机选取 50 名 20-60 岁的 II 级和 III 级肥胖症患者(男女均有)进行研究,他们的平均体重指数分别为 45.63±6.54(男性)和 41.81±5.93kg/m2(女性)。血红蛋白、空腹血糖(FBS)、餐后 2 小时血糖(PP2BS)。血红蛋白 A1c (HbA1c) 血清胰岛素在患者就诊时进行评估,标记为基线,然后在就诊 3 个月时再次进行评估,最后在减肥手术 6 个月后由患者就诊时进行评估。结果显示术后第 3 个月就诊时,血红蛋白水平较基线有明显升高。在术后第 3 个月的随访中,FBS 从基线大幅上升,而在术后第 6 个月的随访中,FBS 又大幅下降。术后 HbA1c 水平较基线显著下降。结论减肥手术后体重指数的改善可能会对糖尿病患者的血糖水平产生积极影响,糖尿病患者有望得到更好的病情控制,并享受更好的生活质量。孟加拉国医学科学杂志》第 23 卷第 01 期 January'24 Page : 29-38
本文章由计算机程序翻译,如有差异,请以英文原文为准。
One Anastomosis Gastric Bypass Surgery: Consequences Over Diabetic Parameters
Introduction: Excessive weight gain in individuals leads to various metabolic disorders, such as diabetes mellitus, contributing to a further increase in body mass index (BMI). Thus, the patient enters a vicious cycle that leads to irreversible health damage. Bariatric surgery has displayed positive outcomes of weight loss with the return of BMI towards normal, which may reduce blood glucose levels to near normal. The remission of diabetes mellitus may be attributed to the reduction in inflammation, improvement of insulin resistance, lowering of peptide YY, and overall improved metabolic state of the body. Methods: One fifty patients, both female and male, in the age group of 20-60 years with grade II and grade III obesity having mean BMI of 45.63±6.54 (male) and 41.81± 5.93kg/m2 (female) were randomly selected for this study. Hemoglobin, Fasting Blood sugar (FBS), 2 hours postprandial blood sugar (PP2BS). Hemoglobin A1c (HbA1c) serum insulin was assessed at the visit, marked as a baseline, then again at the visit 3 months, and finally at the visit by the patient 6 months after bariatric surgery. Results: Hemoglobin level increased significantly from baseline at the 3rd-month post-surgery visit. FBS increased substantially from baseline at the 3rd-month postsurgery visit, which decreased considerably at the 6th-month visit following surgery. HbA1c showed a significant decrease in level from baseline following surgery. Conclusion: Improvement in BMI following bariatric surgery may have a positive impact on blood glucose levels in diabetic patients who may hope to see better management of their condition and may enjoy a better quality of life. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 29-38
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来源期刊
Bangladesh Journal of Medical Science
Bangladesh Journal of Medical Science MEDICINE, GENERAL & INTERNAL-
CiteScore
1.70
自引率
55.60%
发文量
139
审稿时长
24 weeks
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