高血压和 2 型糖尿病患者疾病性质的变化--长期驻扎战区后的平民代表

S. Koval, Maryna Penkova, O. Mysnychenko
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摘要

背景。在现代条件下,医学界面临的一个尖锐问题是战争对慢性非传染性疾病病程的负面影响。其中最常见的是高血压和 2 型糖尿病,它们在大多数情况下是合并症。迄今为止,已经开展了一定数量的工作,研究战争和长期战时应激对高血压发病和进展的影响。但是,对于长期驻扎在战区的患者合并高血压和 2 型糖尿病的病程特点仍未进行研究。目的:研究高血压和 2 型糖尿病患者--平民的代表--在乌克兰哈尔科夫州战区长期滞留后病程性质的变化。材料和方法对 65 名高血压和 2 型糖尿病患者(平民)(男性 30 人,女性 35 人)进行了检查,他们的年龄在 47 至 64 岁之间。所有患者均在战争开始前和在战区逗留 4-5 个月后接受了检查。结果如下患有 2 型糖尿病的高血压患者在进入战区后,高血压变得更加严重(89% 的病例高血压未得到控制,高血压危象和抵抗性高血压的频率显著增加)。此外,还发现碳水化合物代谢失调的频率明显增加。受检患者的脂质代谢紊乱有所发展,并出现了新的心脑血管疾病病例。结论是高血压和 2 型糖尿病患者长期生活在战区对高血压和糖尿病的病程有明显的负面影响,这与心脑血管疾病发病率的显著增加有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes in the nature of the disease in patients with hypertension and type 2 diabetes mellitus — representatives of the civilian population after a long stay in the combat zone
Background. In modern conditions, an acute problem in medicine is the issue of a negative impact of war on the course of chronic noncommunicable diseases. The most common of them are hypertension and type 2 diabetes mellitus, which in most cases occur as a comorbidity. To date, a certain amount of work has been carried out to study the influence of war and chronic wartime stress on the development and progression of hypertension. However, the features of the course of hypertension and type 2 diabetes in case of their combination during a long-term stay of patients in combat zones remain unstudied. The purpose: to study changes in the nature of the disease course in patients with hypertension and type 2 diabetes — representatives of the civilian population after a long stay in the combat zone of the Kharkiv region of Ukraine. Materials and methods. Sixty-five patients (civilians) with hypertension and type 2 diabetes (30 men, 35 women) aged from 47 to 64 years were examined. All of them were examined before the start of the war and 4–5 months after staying in the combat zone. Results. In hypertensive patients with type 2 diabetes after their stay in a combat zone, hypertension became more severe (in 89 % of cases, it was uncontrolled, the frequency of hypertensive crisis and resistant hypertension increased significantly). In addition, a significant increase in the frequency of decompensation of carbohydrate metabolism was detected. The examined patients showed a progression of lipid metabolism disorders and the development of new cases of cardiovascular and cerebrovascular diseases. Conclusions. There was a pronounced negative impact of long-term stay of patients with hypertension and type 2 diabetes in a combat zone on the course of both hypertension and diabetes, which was associated with a significant increase in the incidence of cardiovascular and cerebrovascular diseases.
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