外周组胺给药对大鼠脊髓精氨酸-8-加压素和催产素水平的急性影响。

Endocrinologia experimentalis Pub Date : 1989-09-01

I Jójárt, M Vecsernyés, J Jójárt, F Laczi, G Szabó, G L Kovács, T Janáky, F A László, G Telegdy

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摘要

研究了单次注射20 mg/kg组胺对大鼠脊髓免疫反应性精氨酸-8-抗利尿素(AVP)和催产素(OXT)水平的影响。组胺诱导脊髓AVP含量升高60%，而脊髓OXT含量下降36%。研究结果表明，外周组胺对脊髓AVP和OXT水平的影响存在差异。

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Acute effects of peripheral histamine administration on arginine-8-vasopressin and oxytocin levels in rat spinal cord.

The effects of a single injection of 20 mg/kg histamine on the immunoreactive arginine-8-vasopressin (AVP) and oxytocin (OXT) levels in the rat spinal cord were studied after peripheral (intraperitoneal) administration. Histamine induced a 60% elevation in the AVP content of the spinal cord, whereas the spinal level of OXT decreased by 36%. The findings suggest that peripheral histamine differentially affects the AVP and OXT levels in the spinal cord.

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Endocrinologia experimentalis

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