扩张型心肌病和心肌炎:一个临床病例

O. Onyshchenko, D. Riabenko, O.A. Yepanchintseva
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引用次数: 0

摘要

文章描述了一个合并心肌炎和遗传性扩张型心肌病的临床病例。在一名 40 岁的男子身上,心肌肥大和高房颤首次出现,最初与心肌的炎症过程有关。进一步的基因检查显示,心肌的病理过程还与 FLNC 基因的致病突变和 TNT 基因的突变有关。心肌炎是在家族性(遗传性)扩张型心肌病的背景下发生的。然而,尽管心肌炎治疗和现代药物治疗取得了积极效果,但心肌的病理过程仍在发展。这一临床病例强调了在某些情况下使用基因检测进行全面诊断检查的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dilated cardiomyopathy and myocarditis: a clinical case
The article describes a clinical case of a combination of myocarditis and hereditary dilated cardiomyopathy. In a 40-year-old man cardiomegaly and HF, which occurred for the first time, were initially associated with an inflammatory process in the myocardium. Further genetic examinations showed that pathological processes in the myocardium are also associated with a pathogenic mutation in the FLNC gene and a mutation in the TNT gene. The myocarditis that developed on the background of family (hereditary) dilated cardiomyopathy. However, despite the positive effect of the treatment of myocarditis and contemporary drug therapy, the progression of the pathological process in the myocardium was noted. This clinical case emphasizes the importance of a complete diagnostic examination with the use of genetic testing in certain cases.
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