产后海绵静脉窦血栓形成(CVST):病例报告

Hamida Begum, Lutfunnessa Quddus, Tenku Syed Muhammad Naquib Bin Tenku, Amm Zahurul Quddus, B. A. Allaw
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引用次数: 0

摘要

脑静脉窦血栓形成(CVST)是颅内静脉通路中最严重、最致命的疾病之一,其特点是脑静脉窦中形成血栓。一般来说,脑静脉窦血栓形成是一种暴发性过程,死亡率很高(每 3 名患者中就有 1 名),主要是由于头颈部的细菌感染扩散所致,其中凝固酶阳性葡萄球菌(90%)是主要致病菌。患有高凝状态(即妊娠、产褥期和恶性肿瘤)的患者也可能患上这种形式的血栓。这里我们要介绍的就是这样一个病例,她在产后第 5 天出现 CVST,并伴有持续性头痛和眼部问题。核磁共振成像(MRI)结合磁共振静脉造影(MRV)确诊了该患者。她对低分子量肝素(LMWH)反应良好,出院后长期口服抗凝剂并定期复查。她随后的妊娠顺利,没有再次发生 CVST。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Post-partum cavernous venous sinus thrombosis (CVST): a case report
Cerebral venous sinus thrombosis (CVST) is one of the most serious and fatal disorder of intracranial venous pathways characterized by clot formation in Cerebral venous sinuses. Generally, CVST is a fulminating process with a high rate of mortality (1 in 3 patient) secondary to a spreading bacterial infection specially over head and neck region where coagulase positive Staphylococcus (90%) is mostly responsible. Individuals with  hypercoagulable state i.e., pregnancy or puerperium and malignancy can also suffer from this form of thrombosis. Here we are presenting such a case, who developed CVST on the 5th day of puerperium with features of persistent headache and eye problems. The diagnosis was confirmed with MRI in combination with Magnetic resonance venography (MRV). She responded well to low molecular weight heparin (LMWH) and was discharged on long term oral anticoagulant and regular follow-ups. Her subsequent pregnancy was uneventful without repeat attack of CVST. J Bangladesh Coll Phys Surg 2024; 42: 82-85
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