阴道癌盆腔器官脱垂患者长期使用子宫环的关系

Hamida Begum, M. Rashid, Shamima Haider, F. Zohra
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摘要

阴道癌是妇科癌症中最罕见的一种(0.6%),它与长期使用阴道环形栓有关,长期以来,阴道环形栓一直被用于盆腔器官脱垂(POP)的替代治疗,而非手术治疗。2019 年在科克斯巴扎尔难民营的偏远地区进行了一项调查,在 52 例盆腔器官脱垂病例中,发现 7 例长期使用阴道环形栓,其中 4 例发生了阴道癌。这些患者均为 60 岁以上的老年妇女,未接受随访,表现为阴道出血、不同程度的分泌物和不同程度的疼痛。其中一名患者仅有局部病变--手术切除后进行了放疗;第二名患者 68 岁,接受了新辅助治疗,但在计划手术前死亡。第 3 位患者 79 岁,阴道癌确诊后没有来复查,医生建议她接受明确的手术治疗,但她的家人拒绝手术,她在 2 年后去世,享年 81 岁。第 4 位患者在确诊为阴道癌后拒绝进一步检查和任何形式的治疗。因此,所有盆腔脏器脱垂患者在插入阴道塞之前都应彻底了解情况(包括口头和书面知情同意书),以防潜在的长期严重后果,同时必须确保严格遵守随后的定期随访,对于其中任何可疑的慢性阴道溃疡都必须进行活组织检查。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vaginal Cancer: Association with long term use of Pessary in Pelvic Organ Prolapse
Vaginal cancer, rarest form of gynaecological cancer (0.6%) has been found to be associated with long term use of vaginal ring pessary, which have long been used in alternative management of pelvic organ prolapse (POP) other than surgery. A survey was done in remote areas of Cox’s bazar, refugee camp in 2019 where out of 52 cases of pelvic organ prolapse, 7 cases found to use vaginal ring pessary for long and out of 7, vaginal cancer developed in 4 cases. All of them were aged women above 60 and had defaulted follow up presented with vaginal bleeding, varying discharge and pain of varying intensity. One patient had only local lesion –surgical removal followed by radiotherapy and 2nd one,68 years, received neo-adjuvant therapy and died before planned surgery. The 3rd one, aged 79, did not come for follow up once diagnosis vaginal cancer done and advised for definitive surgical treatment, family refused operation and she passed away after 2 years at 81 years. The 4th one declined further investigations and any form of treatment when diagnosed with vaginal cancer. So, all patients of pelvic organ prolapse should be informed thoroughly (both verbal and written informed consent) before inserting pessary for potential long term serious consequences where strict compliance must be ensured for subsequent regular follow up and biopsy should be mandatory for any suspicious chronic vaginal ulcers among them. J Bangladesh Coll Phys Surg 2024; 42: 78-81
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