TOXICITY OF LEAF AND ROOT EXTRACT OF ANTING-ANTING (Acalypha indica L.) ON MORTALITY OF AEDES AEGYPTI

Dengue Hemorrhagic Fever (DHF) is still one of the main public health problems and often has the status of an Extraordinary Event (KLB) with a high number of cases in a number of regions in Indonesia. Mosquito control with active chemical compounds can be difficult to decompose in nature and cause mosquitoes to become resistant to the next generation. As a substitute, the anting plant (Acalypha indica L.), which has been considered a weed, has bioactive compounds that can be used as natural insecticides. Biological control of vectors by using natural insecticides, a mixture of leaf and root extracts of the anting plant. The study used a mixture of leaf and root extracts of the anting plant using 7 treatments consisting of 5 serial concentrations of 250ppm, 500ppm, 750ppm, 800ppm, and 1000ppm, one positive control group using Aedes and one more negative control using Abate. The concentration that can kill 50% of Aedes aegypti larvae or (LC50) within 24 hours of exposure is 766,000 ppm. The plants contain secondary metabolites such as alkaloids, flavonoids, triterpenoids, and steroids which are toxic to the larvae of the Aedes aegypti mosquito. Keywords:  Acalypha indica L., Aedes aeypti; Toxicity