颅内动脉瘤的治疗:当前趋势与未来方向

IF 3.2 Q2 CLINICAL NEUROLOGY
Aviraj S. Deshmukh, S. Priola, Aris H. Katsanos, G. Scalia, Aderaldo Costa Alves, Abhilekh Srivastava, Christine Hawkes
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引用次数: 0

摘要

颅内动脉瘤是全球健康的一大负担。颅内动脉瘤破裂是一种灾难性事件。如果得不到治疗,在最初的 30 天内死亡率高达 50%。过去三十年来,颅内动脉瘤的治疗方法发生了巨大变化。动脉瘤性蛛网膜下腔出血的医疗管理有所改进,治疗策略也在不断发展。根据可靠的随机对照试验数据,血管内治疗现已成为治疗颅内动脉瘤破裂的主要方法。现在,未破裂颅内动脉瘤的治疗适应症也在扩大,以通过显微外科剪切和血管内治疗防止破裂。显微手术和血管内治疗方式都在不断发展,特别是引入了创新的血管内治疗方案,包括血流分流和骶管内血流阻断。这些新型疗法使临床医生能够治疗更复杂和以前无法治疗的动脉瘤。我们旨在回顾颅内动脉瘤治疗策略随时间推移而发生的演变,并讨论可进一步提高颅内动脉瘤患者治疗安全性和功能预后的新兴技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Management of Intracranial Aneurysms: Current Trends and Future Directions
Intracranial aneurysms represent a major global health burden. Rupture of an intracranial aneurysm is a catastrophic event. Without access to treatment, the fatality rate is 50% in the first 30 days. Over the last three decades, treatment approaches for intracranial aneurysms have changed dramatically. There have been improvements in the medical management of aneurysmal subarachnoid haemorrhage, and there has been an evolution of treatment strategies. Endovascular therapy is now the mainstay of the treatment of ruptured intracranial aneurysms based on robust randomised controlled trial data. There is now an expansion of treatment indications for unruptured intracranial aneurysms to prevent rupture with both microsurgical clipping and endovascular treatment. Both microsurgical and endovascular treatment modalities have evolved, in particular with the introduction of innovative endovascular treatment options including flow diversion and intra-saccular flow disruption. These novel therapies allow clinicians to treat more complex and previously untreatable aneurysms. We aim to review the evolution of treatment strategies for intracranial aneurysms over time, and discuss emerging technologies that could further improve treatment safety and functional outcomes for patients with an intracranial aneurysm.
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来源期刊
Neurology International
Neurology International CLINICAL NEUROLOGY-
CiteScore
3.70
自引率
3.30%
发文量
69
审稿时长
11 weeks
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