Constantinos G. Neochoritis, Eirini Fotopoulou, Alexandros Vasilakis
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MCR-based heteroannulations: A direct access to fused tetrazolo piperazinones and 1,4-diazepanones
Exploiting the chemistry of bifunctional isocyanides, straightforward, rapid and scalable Ugi-tetrazole-based MCR heteroannulations are described. Our synthetic approach provides a series of diverse fused tetrazolo piperazinones and 1,4-diazepanones in just one step.