Usage of corticosteroids as therapeutic agents in diseases

Corticosteroids are class of human-made or synthetic drugs used in almost every medical specialty. They lower inflammation in the body by reducing the production of certain chemicals. At higher doses, corticosteroids also reduce immune system activity. Corticosteroids are commonly prescribed for a variety of indications due to the wide range of effects on the human body. Although they exhibit many therapeutic uses, corticosteroids are, unfortunately, known for their many dose—and duration—dependent toxicities. The purpose of this review is to explore indications for corticosteroid use, mechanism of action, review the toxicity of corticosteroids, and adverse effects and their management.