S. Voskanyan, V. L. Korobka, V. Syutkin, A. R. Monakhov, A. Maltseva, E. Pak, R. V. Korobka, E. I. Kolodyazhny, S. Zubenko, Yu. V. Voskanyan, V. Y. Kotsiyaev
{"title":"一名肝脏受体出现移植物抗宿主疾病。临床观察和文献综述","authors":"S. Voskanyan, V. L. Korobka, V. Syutkin, A. R. Monakhov, A. Maltseva, E. Pak, R. V. Korobka, E. I. Kolodyazhny, S. Zubenko, Yu. V. Voskanyan, V. Y. Kotsiyaev","doi":"10.15825/1995-1191-2023-3-38-49","DOIUrl":null,"url":null,"abstract":"Graft-versus-host disease (GvHD) after liver transplantation (LT) occurs in 0.2–0.3% of liver transplant recipients. Each case is characterized by individual peculiarities of the clinical picture. There are no standards or clinical guidelines for the treatment of GvHD in solid organ recipients; mortality remains very high among these patients. We present two clinical cases of verified GvHD that developed early after LT, and we offer a brief review of the current state of the art in the study of this problem.","PeriodicalId":21400,"journal":{"name":"Russian Journal of Transplantology and Artificial Organs","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development of graft-versus-host disease in a liver recipient. Clinical observations and literature review\",\"authors\":\"S. Voskanyan, V. L. Korobka, V. Syutkin, A. R. Monakhov, A. Maltseva, E. Pak, R. V. Korobka, E. I. Kolodyazhny, S. Zubenko, Yu. V. Voskanyan, V. Y. Kotsiyaev\",\"doi\":\"10.15825/1995-1191-2023-3-38-49\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Graft-versus-host disease (GvHD) after liver transplantation (LT) occurs in 0.2–0.3% of liver transplant recipients. Each case is characterized by individual peculiarities of the clinical picture. There are no standards or clinical guidelines for the treatment of GvHD in solid organ recipients; mortality remains very high among these patients. We present two clinical cases of verified GvHD that developed early after LT, and we offer a brief review of the current state of the art in the study of this problem.\",\"PeriodicalId\":21400,\"journal\":{\"name\":\"Russian Journal of Transplantology and Artificial Organs\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Transplantology and Artificial Organs\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15825/1995-1191-2023-3-38-49\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Transplantology and Artificial Organs","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15825/1995-1191-2023-3-38-49","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Development of graft-versus-host disease in a liver recipient. Clinical observations and literature review
Graft-versus-host disease (GvHD) after liver transplantation (LT) occurs in 0.2–0.3% of liver transplant recipients. Each case is characterized by individual peculiarities of the clinical picture. There are no standards or clinical guidelines for the treatment of GvHD in solid organ recipients; mortality remains very high among these patients. We present two clinical cases of verified GvHD that developed early after LT, and we offer a brief review of the current state of the art in the study of this problem.