基于单萜醇合成芳基巯基膦酸盐中的 3-羟基吡啶和 3-(羟甲基)吡啶

I. Nizamov, A. Yakovlev, I. Nizamov, M. Shulaeva
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引用次数: 0

摘要

以(1R,2S,5R)-(-)-薄荷醇、(1S)-内-(-)-香薄荷醇、外消旋异龙脑和香芹醇为基础,通过 3-羟基吡啶和 3-(羟甲基)吡啶与 O-叔戊基芳基二硫代磷酸反应,获得了 3-羟基吡啶鎓和 3-(羟甲基)吡啶鎓 O-叔戊基芳基二硫代磷酸盐。获得的盐类对蜡样芽孢杆菌和白色念珠菌具有很强的抗菌活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
3-Hydroxypyridine and 3-(Hydroxymethyl)pyridine in the Synthesis of Salts of Aryldithiophosphonic Acids on the Basis of Monoterpenyl Alcohols
3-Hydroxypyridinium and 3-(hydroxymethyl)pyridinium O-terpenyl aryldithiophosphonates were obtained by the reactions of 3-hydroxypyridine and 3-(hydroxymethyl)pyridine with O-terpenyl aryldithiophosphonic acids on the basis of (1R,2S,5R)-(−)-menthol, (1S)-endo-(–)-borneol, racemic isoborneol, and carvacrol. The obtained salts possess high antimicrobial activity against Bacillus cereus and Candida albicans.
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