不同成因缺氧的老年患者红细胞和微循环的变形能力

P. Bejga, S. L. Popel
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引用次数: 0

摘要

在心脏和呼吸衰竭的背景下,与年龄有关的红细胞膜可变形性变化加剧了微循环层面组织和器官的供血障碍,这是导致疾病预后恶化的一个重要因素,尤其是对 60 岁以上的老年人而言。这项工作的目的是研究在老年人心力衰竭和呼吸衰竭的背景下,红细胞膜变形能力的变化规律。在慢性阻塞性肺病和慢性心力衰竭的背景下,老年患者的红细胞膜变形能力下降,并在缺氧的背景下出现相关的微循环障碍。与年龄有关的红细胞膜形态功能状态的生理变化以及在躯体病变(心脏、呼吸衰竭、发热)背景下红细胞膜变形能力的变化导致了相互加重综合征,加剧了微循环层面组织和器官的供血障碍,这是导致疾病预后恶化的重要因素,尤其是对 65 岁以上的老年人而言。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deformability Of Erythrocytes And Microcirculation In Old Patients With Hypoxia Of Various Genesis
Age-related changes in the deformability of erythrocyte membranes against the background of heart and respiratory failure exacerbate disorders of the blood supply to tissues and organs at the microcirculatory level, which is an important factor in worsening the prognosis of the disease, especially in people over 60 years of age. The purpose of the work is to investigate the patterns of changes in the deformability of erythrocyte membranes against the background of heart and respiratory failure in older people. In older patients against the background of COPD and CHF, a decrease in the deformability of erythrocyte membranes and associated microcirculation disorders against the background of hypoxia are detected. Age-related physiological changes in the morpho-functional state of erythrocyte membranes and changes in the deformability of their membranes against the background of somatic pathology (heart, respiratory failure, fever) lead to a syndrome of mutual weighting, exacerbate disorders of the blood supply to tissues and organs at the microcirculatory level, which is an important factor in worsening the prognosis diseases, especially in people over 65 years of age.
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