Muhammad Farhan Mahmud, S. M. Ludin, Wan Ling Lee, Mohamed Saufi Awang
{"title":"气管切开时机(早期和晚期)对严重颅脑损伤患者临床疗效的影响","authors":"Muhammad Farhan Mahmud, S. M. Ludin, Wan Ling Lee, Mohamed Saufi Awang","doi":"10.31436/ijcs.v6i2.305","DOIUrl":null,"url":null,"abstract":"Introduction: Severe head injury patients require a specific treatment plan and nursing care to achieve an optimal clinical outcome. Mild head injury patients may need a few days of hospitalisation for close monitoring and conservative medical administrations. However, in severe head injury cases, the patients may require a more extended period of hospitalisation for a series of complex neuro-medical and neurosurgical management. Tracheostomy may be performed on head injury patients with protracted breathing problems. Early tracheostomy (ET) may improve clinical outcomes late tracheostomy. ET is defined as the tracheostomy done seven days after the initiation of endotracheal intubation. Objective : The objective of this study is to determine the impact of ET on a patient's clinical outcome before being discharged. Methodology: This is a retrospective cohort study involving 45 severe head injury patients with tracheostomy done in two Neuro-Centre hospitals in Klang Valley. The clinical outcome was observed before the participants are discharged including the participant's GCS upon discharge, length of stay (LOS) in the ICU and hospital, the incidence of VAP, duration of mechanical ventilation dependency, and decannulation rate. Findings: There are 45 participants in this study as the sample. Crude analysis performed in this study showed that there is a significant association between tracheostomy classification (early and late) toward participant length of stay in the ICU with a p-value of <0.001, LOS in the hospital (p=0.002), and duration on the mechanical ventilation use (p<0.001) with no association with the GCS upon discharge (p=0.057), the incidence of VAP (p=0.374), and decannulation rate (p=0.081).Potential confounding factors in this study were determined statistically. It was done by comparing the model without an additional factor and the model with an additional factor. Multivariate analysis showed that the association between these variables remained significant for the LOS in the hospital (p=0.035) and duration of mechanical ventilation used (p=0.005). Conclusion: The initiation of ET contributes to a favourable clinical outcome in terms of the duration of mechanical ventilation and length of hospital stay for patients with a severe head injury. However, the association between tracheostomy categorisation and ICU LOS, incidence of pneumonia, decannulation rate, and GCS at discharge was not statistically significant.","PeriodicalId":234583,"journal":{"name":"INTERNATIONAL JOURNAL OF CARE SCHOLARS","volume":"17 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Impact of Tracheostomy Timing (Early and Late) on Severe Head Injury Patients Toward Clinical Outcomes\",\"authors\":\"Muhammad Farhan Mahmud, S. M. Ludin, Wan Ling Lee, Mohamed Saufi Awang\",\"doi\":\"10.31436/ijcs.v6i2.305\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Severe head injury patients require a specific treatment plan and nursing care to achieve an optimal clinical outcome. Mild head injury patients may need a few days of hospitalisation for close monitoring and conservative medical administrations. However, in severe head injury cases, the patients may require a more extended period of hospitalisation for a series of complex neuro-medical and neurosurgical management. Tracheostomy may be performed on head injury patients with protracted breathing problems. Early tracheostomy (ET) may improve clinical outcomes late tracheostomy. ET is defined as the tracheostomy done seven days after the initiation of endotracheal intubation. Objective : The objective of this study is to determine the impact of ET on a patient's clinical outcome before being discharged. Methodology: This is a retrospective cohort study involving 45 severe head injury patients with tracheostomy done in two Neuro-Centre hospitals in Klang Valley. The clinical outcome was observed before the participants are discharged including the participant's GCS upon discharge, length of stay (LOS) in the ICU and hospital, the incidence of VAP, duration of mechanical ventilation dependency, and decannulation rate. Findings: There are 45 participants in this study as the sample. Crude analysis performed in this study showed that there is a significant association between tracheostomy classification (early and late) toward participant length of stay in the ICU with a p-value of <0.001, LOS in the hospital (p=0.002), and duration on the mechanical ventilation use (p<0.001) with no association with the GCS upon discharge (p=0.057), the incidence of VAP (p=0.374), and decannulation rate (p=0.081).Potential confounding factors in this study were determined statistically. It was done by comparing the model without an additional factor and the model with an additional factor. Multivariate analysis showed that the association between these variables remained significant for the LOS in the hospital (p=0.035) and duration of mechanical ventilation used (p=0.005). Conclusion: The initiation of ET contributes to a favourable clinical outcome in terms of the duration of mechanical ventilation and length of hospital stay for patients with a severe head injury. However, the association between tracheostomy categorisation and ICU LOS, incidence of pneumonia, decannulation rate, and GCS at discharge was not statistically significant.\",\"PeriodicalId\":234583,\"journal\":{\"name\":\"INTERNATIONAL JOURNAL OF CARE SCHOLARS\",\"volume\":\"17 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"INTERNATIONAL JOURNAL OF CARE SCHOLARS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31436/ijcs.v6i2.305\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"INTERNATIONAL JOURNAL OF CARE SCHOLARS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31436/ijcs.v6i2.305","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
导言:重度颅脑损伤患者需要特定的治疗计划和护理,以达到最佳临床效果。轻度颅脑损伤患者可能需要住院几天,接受密切监测和保守治疗。但是,对于重度颅脑损伤病例,患者可能需要延长住院时间,接受一系列复杂的神经内科和神经外科治疗。对于有长期呼吸困难的头部受伤患者,可以实施气管切开术。早期气管切开术(ET)可改善晚期气管切开术的临床效果。ET 的定义是在开始气管插管七天后进行气管切开术。目的:本研究的目的是确定 ET 对患者出院前临床疗效的影响。研究方法:这是一项回顾性队列研究,涉及巴生谷两家神经中心医院的 45 名气管切开的严重颅脑损伤患者。研究人员观察了患者出院前的临床结果,包括出院时的 GCS、在重症监护室和医院的住院时间(LOS)、VAP 的发生率、依赖机械通气的时间以及拔管率。研究结果本研究以 45 名参与者为样本。本研究进行的粗略分析表明,气管切开术分类(早期和晚期)与参与者在重症监护室的住院时间(P值<0.001)、住院时间(P=0.002)和使用机械通气的持续时间(P<0.001)有显著关联,与出院时的GCS(P=0.057)、VAP发生率(P=0.374)和拔管率(P=0.081)无关联。通过比较无额外因素模型和有额外因素模型,确定了本研究中的潜在混杂因素。多变量分析表明,在住院时间(P=0.035)和使用机械通气时间(P=0.005)方面,这些变量之间的关系仍然显著。结论就机械通气持续时间和住院时间而言,对严重颅脑损伤患者启动 ET 有助于获得良好的临床结果。然而,气管切开术分类与重症监护室住院时间、肺炎发生率、拔管率和出院时 GCS 之间的关系在统计学上并不显著。
The Impact of Tracheostomy Timing (Early and Late) on Severe Head Injury Patients Toward Clinical Outcomes
Introduction: Severe head injury patients require a specific treatment plan and nursing care to achieve an optimal clinical outcome. Mild head injury patients may need a few days of hospitalisation for close monitoring and conservative medical administrations. However, in severe head injury cases, the patients may require a more extended period of hospitalisation for a series of complex neuro-medical and neurosurgical management. Tracheostomy may be performed on head injury patients with protracted breathing problems. Early tracheostomy (ET) may improve clinical outcomes late tracheostomy. ET is defined as the tracheostomy done seven days after the initiation of endotracheal intubation. Objective : The objective of this study is to determine the impact of ET on a patient's clinical outcome before being discharged. Methodology: This is a retrospective cohort study involving 45 severe head injury patients with tracheostomy done in two Neuro-Centre hospitals in Klang Valley. The clinical outcome was observed before the participants are discharged including the participant's GCS upon discharge, length of stay (LOS) in the ICU and hospital, the incidence of VAP, duration of mechanical ventilation dependency, and decannulation rate. Findings: There are 45 participants in this study as the sample. Crude analysis performed in this study showed that there is a significant association between tracheostomy classification (early and late) toward participant length of stay in the ICU with a p-value of <0.001, LOS in the hospital (p=0.002), and duration on the mechanical ventilation use (p<0.001) with no association with the GCS upon discharge (p=0.057), the incidence of VAP (p=0.374), and decannulation rate (p=0.081).Potential confounding factors in this study were determined statistically. It was done by comparing the model without an additional factor and the model with an additional factor. Multivariate analysis showed that the association between these variables remained significant for the LOS in the hospital (p=0.035) and duration of mechanical ventilation used (p=0.005). Conclusion: The initiation of ET contributes to a favourable clinical outcome in terms of the duration of mechanical ventilation and length of hospital stay for patients with a severe head injury. However, the association between tracheostomy categorisation and ICU LOS, incidence of pneumonia, decannulation rate, and GCS at discharge was not statistically significant.