肾脓肿:一家儿科转诊医院的经验

Marian Chacoff, Sabrina Schiavino, María Soledad Tineo, C. I. Cazes, Eduardo Luis López
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摘要

背景:肾脓肿在儿科并不常见,其临床和实验室检查结果无特异性。当怀疑有肾脓肿时,影像学检查对确诊至关重要。目的:描述儿科肾脓肿的临床流行病学、微生物学、诊断和治疗特点。方法 :对里卡多-古铁雷斯儿童医院感染性疾病科 9 年间接诊的肾脓肿住院患者进行回顾性和描述性研究。统计分析:Epi Info 7.2.2.6。结果:共纳入 15 名患者(67% 为男性),中位年龄为 9 岁(范围 [r] 0.7-17)。四名患者患有基础疾病。最常见的症状是发烧,中位持续时间为 10 天(r:1-36),其次是腰痛。白细胞计数中位数为 15,700 个/毫米 3(r:7,100-45,000),CRP 为 193 毫克/升(r:1-362)。4 名患者的尿液培养呈阳性:2 名大肠埃希菌、1 名肺炎克雷伯菌和大肠埃希菌、1 名白色念珠菌和肺炎克雷伯菌。没有患者出现菌血症。脓肿的诊断由超声波确诊。7 名患者接受了手术引流,其中 2 例分离出金黄色葡萄球菌,1 例分离出铜绿假单胞菌。静脉抗生素治疗的中位数为 16 天(r:7-49),总计 28 天(r:14-91)。一名患者需要转入重症监护室,两名患者需要进行肾切除术。结论 :肾脓肿在儿科并不常见,但其发病率和死亡率却很高。尿路感染(UTI)患者如果病情发展缓慢,持续发热且无抗生素反应,则应怀疑肾脓肿。在我们的研究中,肾脏超声波的灵敏度很高,可以早期诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Abscesos renales: experiencia en un hospital pediátrico de referencia
Background : Renal abscesses are infrequent in pediatrics, with nonspecific clinical and laboratory findings. When suspected, imaging is essential to establish the diagnosis. Aim: To describe the clinical-epidemiological, microbiological, diagnostic and therapeutic characteristics of renal abscesses in pediatrics. Methods : Retrospective and descriptive study of hospitalized patients with renal abscess, followed by Infectious Diseases Department of Ricardo Gutiérrez Children’s Hospital during 9 years. Statistical analysis: Epi Info 7.2.2.6. Results : 15 patients (67% male), median age 9 years (range [r] 0.7-17) were included. Four patients had underlying disease. The most frequent symptom was fever, with a median duration of 10 days (r:1-36), followed by lumbar pain. The median white blood cell count was 15,700/ mm 3 (r: 7,100-45,000) and CRP 193mg/L (r: 1-362). Four patients presented positive urine culture: 2 Escherichia coli , 1 Klebsiella pneumoniae and E. coli and 1 Candida albicans and K. pneumoniae . No patient had bacteremia. The diagnosis of abscess was confirmed by ultrasound. Surgical drainage was performed in 7 patients, with isolation of Staphylococcus aureus in 2 and Pseudomonas aeruginosa in 1. Empirical treatment included 3 rd generation cephalosporin, combined in 67% of cases. The median of intravenous antibiotic therapy was 16 days (r: 7-49) with a total of 28 days (r:14-91). One patient required transfer to intensive care unit and 2 nephrectomy. Conclusion : Renal abscesses are infrecuent in pediatrics, but they present significant morbidity and mortality. It should be suspected in patients with urinary tract infection (UTI)with torpid evolution that persists with fever without antibiotic response. In our study, the high sensitivity of renal ultrasound allowed early diagnosis.
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