监测和调查马赞达兰省尿路感染中分离出的溶血性葡萄球菌的抗性基因 gyrA、parC、blaZ、ermA、ermB 和 ermC

Q4 Medicine

Infection Epidemiology and Microbiology Pub Date : 2023-08-01 DOI:10.61186/iem.9.2.117

Reyhaneh Amiri, Majid Alipour, Ali Khajir Engasi, Ali Reza Amiri, Ramin Mofarrah

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引用次数: 0

摘要

背景：由于抗生素耐药菌种的发展，所有年龄段的人群都可观察到细菌性尿路感染。本研究旨在调查伊朗马赞达兰省从尿路感染（UTIs）患者中分离出的水肿葡萄球菌的耐药基因回旋酶亚基 A（gyrA）、拓扑异构酶 IV（parC）亚基基因、β-内酰胺酶（blaZ）、红霉素核糖体甲基化酶（ermC）、ermB 和 ermA。材料与方法：在这项横断面描述性研究中，从 2022 年 4 月至 12 月期间收集了 3280 份马赞达兰省尿路感染患者的临床样本。通过生化检验对分离菌进行鉴定。根据临床与实验室标准协会（CLSI）指南，采用磁盘扩散法进行微生物敏感性检测。聚合酶链反应（PCR）用于检测耐药基因的存在。研究结果在收集到的 3280 份临床样本中，有 2088 份样本通过生化检验检测到了属一级的细菌

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Monitoring and Investigation of Resistance Genes gyrA, parC, blaZ, ermA, ermB, and ermC in Staphylococcus saprophyticus Isolated from Urinary Tract Infections in Mazandaran Province

Background: Bacterial urinary tract infections are observed in all age groups due to the development of antibiotic-resistant species. This study aimed to investigate resistance genes gyrase subunit A ( gyrA) , topoisomerase IV ( parC ) subunit gene, beta lactamase ( blaZ ), erythromycin ribosome methylase ( ermC ), ermB , and ermA in Staphylococcus saporophyticus isolated from patients with urinary tract infections (UTIs) in Mazandaran Province, Iran. Materials & Methods: In this cross-sectional descriptive study, 3280 clinical samples were collected from patients with UTIs in Mazandaran Province from April to December 2022. Isolates were identified by biochemical tests. Microbial sensitivity tests were performed by disk diffusion method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. Polymerase chain reaction (PCR) was used to check the presence of resistance genes. Findings: Out of a total of 3280 clinical samples collected, 2088 samples were detected by biochemical tests at the genus level

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来源期刊

Infection Epidemiology and Microbiology Medicine-Epidemiology

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

6 weeks