作为蛔虫感染标志物的血液嗜酸性粒细胞水平诊断测试

Said Munazar Rahmat, Merina Panggabean, Aman Agustinus Depari, Teuku Romi, Imansyah Putra, Dhiatama Endalif
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引用次数: 0

摘要

瘤蛔虫感染是印度尼西亚17种被忽视的热带疾病之一。但是,印尼的蛔虫感染常常得不到诊断。这是因为使用卡托-卡茨(Kato-Katz)方法进行粪便检查的情况仍然很少。因此,需要一种更实用且可常规进行的替代检查方法。本研究是一项用于诊断蛔虫感染的血液伊红水平诊断测试。这项研究在棉兰的一家医院进行。这项研究涉及 63 名儿童,他们都得到了家长的同意。儿童粪便采用卡托-卡茨法(Kato-Katz method)作为金标准进行检测,血液中的埃希氏菌(eosinofil)水平则作为本研究的一项指标进行检测。结果显示,埃希诺菲尔的灵敏度为 25%,特异度为 96.08%,阳性预测值为 60%,阴性预测值为 84%,阳性似然比为 6.38%,阴性似然比为 0.78%。结论是血液中的埃索菲水平升高不能作为卡托-卡茨(Kato-Katz)诊断疟原虫感染的替代检测方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnostic Test of Blood Eosinophil Level as a Marker of Ascaris lumbricoides Infection
A. lumbricoides infection is one from 17 neglected tropical diseases in Indonesia. But, Infection of A. lumbricoides in Indonesia often undiagnosed. This is because stool examination with Kato-Katz’s method still rarely done. So it needs something alternative examination that more practical and can be routinely carried out. This study was a diagnostic test for blood eosinofil levels in diagnosing A. lumbricoides infection. This research was conducted at a hospital in Medan. This study involved 63 children who had their parents approval. Children stool were examined by Kato-Katz method as a gold standard and blood eosinofil levels was examined as an index in this study. The results showed sensitivity level of eosinofil is 25% and specificity 96,08%, positive predictive value 60%, negative predictive value 84%, positive likelihood ratio 6,38% and negative likelihood ratio 0,78%. The conclusion is elevated blood eosinofil levels cannot be used as an alternative test Kato-Katz in diagnosing Infection of A. lumbricoides.
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