健康年轻人峰值呼气流速的季节模式

N. Mahotra, Sonam Chaudhary, S. Pradhan
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摘要

背景:季节变化与包括呼气峰流速(PEFR)在内的肺功能变化有关。这些变化在不同人群和地区有所不同。因此,本研究旨在评估加德满都健康年轻人呼气峰流速的季节性变化。研究方法对 Maharajgunj 医学院临床生理学系的 60 名医学本科生进行了对比研究。研究采用方便抽样技术选取学生,在获得知情同意后,在适当培训的帮助下使用赖特峰流速仪记录 PEFR。在 2023 年冬季(1 月至 2 月)的早晨和白天,以及在 2023 年夏季(5 月至 6 月)的每天同一时间,对同一参与者进行了两次 PEFR 记录。数据使用 SPSS-16 版本进行分析,并使用配对 T 检验比较冬季和夏季 PEFR 的平均变化。结果在所有参与者中,夏季早晨的 PEFR(499.50±89.50 L/min)高于冬季早晨的 PEFR(487.50±86.09 L/min),男性参与者的 PEFR(567.33±69.34;550.83±69.58)也高于冬季早晨的 PEFR(567.33±69.34;550.83±69.58)。同样,在所有参与者中,夏季白天的 PEFR(505.08±88.85 L/min)相对高于冬季白天的 PEFR(491.27±92.07 L/min),差异有统计学意义(P 值<0.05)。男性参与者在冬季和夏季的肺活量以及所有参与者在夏季的肺活量均显示存在昼夜变化,且具有统计学意义。结论PEFR存在季节和昼夜变化。因此,临床医生应注意,冬季和早晨记录的肺活量可能分别低于夏季和白天记录的肺活量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Seasonal Patterns of Peak Expiratory Flow Rate in Young Healthy Individuals
Background: The seasonal changes are associated with changes in pulmonary functions including Peak Expiratory Flow Rate (PEFR). These changes are different among different population and location. This study thus aimed to evaluate the seasonal variations in PEFR among healthy young individuals in Kathmandu. Methods: A comaparative study was carried out among 60 undergraduate medical students of Maharajgunj Medical Campus in the department of Clinical Physiology. The students were selected by convenient sampling technique and after obtaining the informed consent, the PEFR was recorded with the help of Wright’s peak flow meter with proper training. The PEFR was recorded two times i.e. morning and daytime hours in winter season (January-February) 2023 and also in same daily hours of summer season (May-June) 2023 in the same participants. The data were analyzed using SPSS-16 version and the paired T test was used to compare the mean changes in PEFR in winter and in summer seasons. Results: The PEFR in summer morning (499.50±89.50 L/min) was recorded higher than in winter morning (487.50±86.09 L/min) among total participants and also in male participants (567.33±69.34; 550.83±69.58) which was statistically significant with P value <0.05. Similarly, the PEFR in summer daytime (505.08±88.85 L/min) was comparatively more than in winter daytime (491.27±92.07 L/min) which was statistically significant among all participants with P value <0.05. The PEFR in the winter and summer seasons of male participants and in the summer of total participants showed the existence of diurnal variation which was statistically significant. Conclusions: There is seasonal variation as well as diurnal variations of PEFR. So, the clinicians should be aware that the PEFR recorded in winter season and in the morning time might be less than that recorded in the summer and at the daytime respectively.
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