Gastrointestinal Stromal Tumor of Esophageal Location: A Rare Case with Surgical Discussion. Case Report and Literature Review

Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms. They arise from the intestinal wall and usually present as subepithelial neoplasms in the stomach and small intestine; however, they can appear anywhere in the gastrointestinal (GI) tract. Most of these tumors have mutations in KIT or platelet-derived growth receptor alpha (PDGFRA), while mutations in succinate dehydrogenase (SDH) or other genes are less frequent. New molecules have shown promising results in the therapy of these tumors.