Berchemia lineata (L.) DC根提取物和化合物对黄嘌呤氧化酶的抑制能力

Quang Ung Le, Thi-Ngoc Lanh
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引用次数: 0

摘要

在越南,Berchemia lineata (L.) DC 的根被用于治疗类风湿性关节炎。这项工作研究了根提取物的化学成分和对黄嘌呤氧化酶抑制能力的评估。经鉴定,根中含有槲皮素和大黄素两种化合物。茜草素 6-O-α-L-鼠李糖基-(1→6)-O-β-D-吡喃葡萄糖苷(化合物 2)是首次在根中发现的新化合物。与槲皮素、大黄素和 E70 相比,化合物 2 对黄嘌呤氧化酶的抑制能力最强。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inhibitory capacity of enzyme xanthine oxidase of extract and compounds from roots of Berchemia lineata (L.) DC
The root of Berchemia lineata (L.) DC is used to treat rheumatoid arthritis in Vietnam. The chemical compounds and evaluation of the xanthine oxidase inhibitory capacity of root extracts were studied in this work. Two compounds of quercetin and emodin were the identified compounds in the roots. Rubrofusarin 6-O-α-L-rhamnosyl-(1 → 6)-O-β-D-glucopyranoside (compound 2) being new compounds was firstly identified in the roots. The compound 2 has highest xanthine oxidase enzyme inhibitory capacity compared to quercetin, emodin and E70.
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