早期诊断睡眠呼吸暂停患者精神障碍的意义

Anwesha Banerjee, Divya Pandya, Arpita Maitra, Snehasish Basu, Ashish Rao, Priyanka Dausage
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引用次数: 0

摘要

阻塞性睡眠呼吸暂停(OSA)是一种因睡眠时呼吸系统紊乱而导致的衰弱性疾病。目前,OSA 与情绪(尤其是抑郁和焦虑)之间的关系尚不明确。本文旨在阐明这种关系。目前迫切需要更好地了解心理疾病在 OSA 中的作用。需要进行精心设计的纵向研究,以检查 OSA 与心理疾病之间的时间关系,还需要进一步研究,以确定混杂因素和性别等效应调节因素在任何明显关系中的作用。建议睡眠临床医生将心理疾病视为嗜睡和疲劳的可能原因。有人提出了几种可能将 OSA 与抑郁症联系起来的因果机制,但尚未得到证实。与仅患有 OSA 的患者相比,同时患有抑郁症和 OSA 的患者的情况似乎更糟,而且在治疗 OSA 的短期研究中,至少有一些患者的抑郁症状持续存在。直接治疗 OSA 的心理疾病可能会提高患者对治疗的接受程度,减少嗜睡和疲劳,改善生活质量,但要回答这个问题,还需要进行干预试验。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SIGNIFICANCE OF EARLY DIAGNOSIS OF PSYCHIATRIC DISORDERS IN SLEEP APNEA PATIENTS
Obstructive Sleep Apnea (OSA) is a debilitating condition stemming from disruption to the respiratory system during sleep. At present, the nature of the relationship between OSA and mood, specifically depression and anxiety, is still unclear. The purpose of this paper is to shed some light on this relationship. There is an urgent need to better understand the roles of psychological illness in OSA. Well-designed longitudinal studies are needed to examine temporal  relationships between the OSA, and psychological diseases and further research is needed to establish the role of confounders, and effect modifiers such as gender, in any apparent relationship. Sleep clinicians are advised to consider psychological diseases a likely cause of sleepiness and fatigue. Several possible causal mechanisms linking OSA, and depression have been proposed but not established. Patients who have depression as well as OSA appear worse off than those with OSA only, and depressive symptoms persist in at least some patients in short term studies of treatment forOSA. Direct treatment of psychological diseases in OSA might improve acceptance of therapy, reduce sleepiness, and fatigue and improve quality of life, but intervention trials are required to answer this question.
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