PAPER AND THIN-LAYER CHROMATOGRAPHY IN THE IDENTIFICATION OF HYDROXYCINNAMIC ACIDS IN PLANT RAW MATERIALS (REVIEW). MESSAGE 1

Hydroxycinnamic acids (HCC) are one of the types of biologically active compounds (BAC) synthesized by plants. Along with carbohydrates and proteins, HCCs are the most common compounds in the plant world and are found in almost all higher plants in free form, as part of esters and glycosides. Although the pharmacological activity of most HCCs has not been studied enough yet, however, its spectrum is quite wide. Many wild plants, which are currently used mainly in ethnoscience and traditional medicine, are cheap, affordable raw materials that are promising for introduction into the medical and pharmaceutical practice of our country as potential medicines. Therefore, the search for new plant species that are interesting for detailed study and the creation of modern medicines containing HCC on their basis is an scientific research area of current interest. The review is devoted to the study and systematization of paper and thin-layer chromatography methods used to determine the composition of HCC in plant raw materials growing on the territory of the Russian Federation as a potential raw material base of polyphenolic compounds. The review uses 80 sources of domestic scientific literature for the period from 2007 to 2022 inclusive, which show the results of the use of thin-layer (TLC) and paper (PC) chromatography for the study, identification and standardization of plant raw materials by the content of hydroxycinnamic acids (HCC). The research method used was a retrospective information and analytical analysis of the of Russian scientific literature sources.