细菌引起的尿路感染概述

Khudhur Hr
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引用次数: 0

摘要

尿路感染(UTI)是一个重要的公共卫生问题,可由多种细菌引起,包括大肠埃希菌、变形杆菌、粪肠球菌、肺炎克雷伯菌和无菌葡萄球菌。尿路病原体的高复发率和不断演变的抗生素耐药性对这些疾病的经济负担构成了严重威胁。尿液中的病原体可通过多种诊断方法检测出来,这些方法大致分为实验室检测法和护理点检测法(POC)。由于传统方法耗时较长,许多研究机构和公司都致力于建立快速准确的病原体鉴定方法。适应症和症状可进一步分为以下三类:(1) 发烧等一般体征和症状;(2) 尿急、尿频和排尿困难等下尿路症状;(3) 恶心和乏力等非特异性体征和症状。此外,由多药耐药性(MDR)引起的尿毒症发病率正在上升,这对抗生素耐药性的传播以及这些感染造成的经济负担产生了相当大的负面影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Overview of Urinary Tract Infection Caused by Bacteria
Urinary tract infections (UTIs), a significant public health concern, can be brought on by a wide variety of bacteria, including Escherichia coli, Proteus mirabilis, Enterococcus faecalis, Klebsiella pneumoniae, and Staphylococcus saprophyticus. The high recurrence rates and evolving antibiotic resistance of uropathogens constitute a serious threat to the financial burden of these disorders. Pathogens in urine can be detected using a variety of diagnostic approaches, which are broadly divided into laboratory-based and point-of-care (POC) detection methods. Many research institutions and companies working in this subject have strived to establish rapid and accurate pathogen identification because traditional approaches may be timeconsuming. The indications and symptoms are further divided into the following three groups: (1) General signs and symptoms like fever; (2) lower urinary tract symptoms including urgency, frequency, and dysuria; (3) non-specific signs and symptoms such nausea and malaise. Additionally, the prevalence of UTIs brought on by multidrug resistance (MDR) is rising, which has a considerable negative impact on the propagation of antibiotic resistance as well as the financial burden of these infections
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