Antibiotic Efficacy of Commercially Available Antibiotics on Indigenous Microbes Isolated from Rotten Fruits

The human commonly consume fruits as food. Indigenous microbes are responsible for the spoilage of fruits. If bacteria spoil consumed fruit, they can cause infections in the human body that may lead to severe consequences. Some commercially available drugs are effective against an infection, and some show no or little effect. Objective: To check the efficacy of locally available drugs against indigenous microbes that are commonly responsible for infections in natives. Methods: Microbes isolated from rotten fruits are used to check that the antibiotics available in our market are effective against them. Different antibiotics are used against these bacteria. Control antibiotics determine the efficacy of each antibiotic. Results: All the antibiotics are effective but to a different extent. The presence of the active compound in the drug determines its effectiveness. If the active compound is present in pure form and adequate amounts in the dosage of the drug, it will be effective. Bacteria become resistant to the drugs, which is the major issue faced. Conclusions: Antibiotic resistance and specificity of drugs are also important factors that determine the efficacy of the drugs. Antibiotic resistance is influenced by the uncontrolled, unnecessary, and recommended use of antibiotics in society. The specificity of the drug to the microbes also contributes to the effectiveness of antibiotics.