Ilgam Gaisin, I. Islamov, L. Dzhemileva, U. Dzhemilev
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引用次数: 0
摘要
以(5 Z ,9 Z )-十四碳-5,9-二烯-1,14-二酸为基础，合成了以前未曾描述过的聚醚芳香族大环二醇化合物，收率良好（53-67%）。所得大环化合物在体外对肿瘤 Jurkat 细胞的细胞毒性
Synthesis of Aromatic Macrodiolides and Study of Their Antitumor Activity In Vitro
: Based on (5 Z ,9 Z )-tetradeca-5,9-diene-1,14-dioic acid, previously undescribed polyether aromatic macrodiolides were synthesized in good yields (53–67%). The cytotoxicity of the resulting macrocyclic compounds in vitro against tumor Jurkat cells
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