下壁心肌梗死患者的右心室梗死及其与各种风险因素的关系

IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Hafeez Orakzai, Danish Ahmed, Tashfeen Tashfeen, Nazeef Nazeef
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引用次数: 0

摘要

研究目的本研究旨在评估下壁心肌梗死患者中右室梗死的发生率以及导致右室受累的风险因素。 研究方法:一项前瞻性研究于 2022 年 12 月至 2023 年 7 月在白沙瓦的 Hayatabad 综合医疗中心进行,涉及 114 名年龄在 40-80 岁之间的下壁心肌梗死患者。研究通过胸痛、心电图变化和心肌酶升高来确认心肌梗死,而右心室梗死则通过特定的心电图导联进行评估。有特殊病史的患者被排除在外。为确保患者权利和数据保密性,该研究获得了伦理批准。 结果在 114 名下壁心肌梗死(MI)患者中,42 人(36.8%)患有右心室梗死(RVI)。RVI 和年龄:大多数参与者(59.6%)的年龄在 40 至 60 岁之间,其余参与者(40.4%)的年龄在 61 至 80 岁之间。RVI 的发生与年龄无明显关系(p = 0.707)。RVI 与性别:参与者中 61.4% 为男性,38.6% 为女性。男性 RVI 发病率(45.7%)明显高于女性(22.7%),P 值为 0.013。 40.3%的参与者患有高血压,而 RVI 与高血压有显著相关性(p < 0.001)。65.2%的高血压患者出现 RVI,而非高血压患者中只有 17.6%出现 RVI。吸烟:有 26.3% 的参与者吸烟,吸烟者(56.7%)的 RVI 发病率明显高于非吸烟者(29.8%),P 值为 0.008。糖尿病:21.0% 的患者患有糖尿病,RVI 与糖尿病有显著相关性(p = 0.014)。58.3% 的糖尿病患者出现 RVI,而非糖尿病患者仅为 31.1%。血脂异常:12.3%的患者存在血脂异常,但与 RVI 的关系无统计学意义(p = 0.092)。57.1%的血脂异常患者和 34.0%的非血脂异常患者出现 RVI。 结论约 33% 的 IWMI 患者会出现 RVI。识别风险因素对于评估慢性心脏病患者至关重要。使用这种简单易行的方法有可能简化在下壁心肌梗死的情况下识别和分类高危人群的过程。这项研究的风险变量包括高血压、糖尿病和吸烟。在这三个选项中,高血压患者发生右心室梗死的可能性最大。因此,可以推断这一因素是免疫系统受损者发生呼吸道病毒感染的最主要风险因素之一。对上述风险因素采取及时的管理策略将减少呼吸道病毒感染的发生,从而减轻相关并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Right Ventricular Infarction in Patients with Inferior Wall Myocardial Infarction and its Association with Various Risk Factors
Objectives: This study aimed to evaluate the occurrence of right ventricular infarction among patients with inferior wall MI and the risk factors leading to involvement of the right ventricle. Methodology: A prospective study was conducted at Hayatabad Medical complex in Peshawar from December 2022 to July 2023, involving 114 participants aged 40-80 years with inferior wall myocardial infarction. The study confirmed MI by chest pain, ECG changes, and elevated cardiac enzymes, while right ventricular infarction was assessed through specific ECG leads. Patients with specific medical histories were excluded. Ethical approval was obtained to ensure patient rights and data confidentiality. Results: Out of 114 patients with inferior wall myocardial infarction (MI), 42 (36.8%) had right ventricular infarction (RVI). RVI and Age: Most participants (59.6%) were aged 40 to 60 years, and the rest (40.4%) were aged 61 to 80 years. RVI occurrence was not significantly associated with age (p = 0.707). RVI and Gender: Among the participants, 61.4% were male, and 38.6% were female. RVI was significantly more common in males (45.7%) compared to females (22.7%) with a p-value of 0.013. Hypertension was present in 40.3% of participants, and RVI was significantly associated with hypertension (p < 0.001). RVI occurred in 65.2% of hypertensive patients compared to 17.6% of non-hypertensive patients. Smoking: Smoking was reported by 26.3% of participants, and RVI was significantly more prevalent among smokers (56.7%) compared to non-smokers (29.8%) with a p-value of 0.008. Diabetes Mellitus: Diabetes was present in 21.0% of patients, and RVI was significantly associated with diabetes (p = 0.014). RVI occurred in 58.3% of diabetic patients versus 31.1% in non-diabetics. Dyslipidemias: Dyslipidemia was found in 12.3% of patients, but the association with RVI was not statistically significant (p = 0.092). RVI occurred in 57.1% of dyslipidemic patients and 34.0% of non-dyslipidemic patients. Conclusion: The occurrence of RVI is seen in around 33% of instances in conjunction with IWMI. The identification of risk factors is crucial in the assessment of individuals with chronic heart disease. The use of this straightforward method has the potential to streamline the process of identifying and categorizing individuals who may be at a higher risk of developing right ventricular infarction in the context of inferior wall myocardial infarction. The risk variables included in this study consist of hypertension, diabetes mellitus, and smoking. Among these three options, people with hypertension have the greatest likelihood of experiencing RVI. Therefore, it may be inferred that this factor is among the most significant risk factors for respiratory viral infections in individuals with impaired immune systems. The use of timely management strategies for the aforementioned risk factors will lead to a decrease in the occurrence of RVI and therefore mitigate the related complications.
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来源期刊
Pakistan Heart Journal
Pakistan Heart Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
0.20
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64
审稿时长
6 weeks
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