中性粒细胞与淋巴细胞比值的作用及其与非 ST 段抬高型急性冠状动脉综合征患者的常见临床结果的关系

IF 0.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Javaid Jalbani, K. I. Bhatti, Tariq Sallar
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引用次数: 0

摘要

目的评估入院时中性粒细胞与淋巴细胞比值(NLR)对非 ST 段抬高急性冠状动脉综合征(Non-ST-ACS)患者院外结局和并发症的风险分层作用。 研究方法方法:我们招募了连续的非 ST-ACS 患者。获得 NLR,并根据 6.0 分别将其分为低危、中危和高危。记录新的 ST-T 变化、心律失常、造影剂诱发肾病(CIN)和死亡率。 结果结果:结果:346 名患者的中位 NLR 为 3 [2.1-5.3],其中高危和中危组分别占 19.9% 和 30.6%。3.5%(12 例)的患者出现新的 ST-T 改变,其中低危、中危和高危组分别为 8 例、3 例和 1 例(P = 0.424)。5.8%(20 人)的患者出现心律失常,其中低危、中危和高危组分别有 7、5 和 8 人(P = 0.067)。4.9%(17 例)的患者观察到 CIN,低、中、高风险组分别为 5、5 和 7 例(P = 0.064)。院内死亡率为 1.4%(5 例),高危组和低危组分别为 2 例和 3 例(P = 0.260)。 结论大量非 ST-ACS 患者属于 NLR 高危类别。虽然 NLR 与院内死亡率和不良事件之间的关系没有统计学意义,但观察到高风险组的不良事件发生率相对较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Role of Neutrophil to Lymphocytes Ratio and It's Common Clinical Outcomes Amount the Patient with Non ST Elevation Acute Coronary Syndrome
Objectives: To evaluate the admission neutrophil-to-lymphocyte ratio (NLR) for risk stratification for in-hospital out-comes and complications in non-ST-elevation acute coronary syndrome (non-ST-ACS) patients. Methodology: Methods: We recruited consecutive patients with non-ST-ACS. The NLR was obtained and stratified as low, inter- mediate, and high-risk based on <3.0, 3.0e6.0, and >6.0, respectively. The new ST-T changes, arrhythmias, contrast-induced nephropathy (CIN), and mortality were recorded. Results: Results: Median NLR was 3 [2.1-5.3] for 346 patients with 19.9% and 30.6% in high- and intermediate-risk group. New  ST-T changes were observed in 3.5% (12) out of which 8, 3, and 1 patient in low, intermediate, and high-risk group (p = 0.424), respectively. Arrhythmias were observed in 5.8% (20) with 7, 5, and 8 patients in low, intermediate, and high- risk group (p = 0.067), respectively. CIN was observed in 4.9% (17) with 5, 5, and 7 in low, intermediate, and high-risk group (p = 0.064), respectively. In-hospital mortality was recorded in 1.4% (5) with 2 and 3 patients in high and low-risk group (p = 0.260), respectively. Conclusion: A significant number of non-ST-ACS patients fall in the high-risk category of NLR. Although, the association between NLR and in-hospital mortality and adverse events was not statistically significant but relatively higher rates of events were observed in high risk group.
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来源期刊
Pakistan Heart Journal
Pakistan Heart Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
0.20
自引率
0.00%
发文量
64
审稿时长
6 weeks
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