Ester Lopes de Melo, Bruno Augusto Machado Tavares, Nayara Nílcia Dias Colares, Aline Lopes do Nascimento, H. Carvalho, Andrés Navarrete Castro, Arlindo César Matias Pereira, Carlos Eduardo Winter, I. D. S. Sena, Luiz Fernando Moreira, J. C. T. Carvalho
{"title":"Euterpe oleracea、Bixa orellana、Myciaria dubia 和 Astrocaryum aculeatum(Terasen® Nutraceutical)的结合可延长秀丽隐杆线虫的寿命","authors":"Ester Lopes de Melo, Bruno Augusto Machado Tavares, Nayara Nílcia Dias Colares, Aline Lopes do Nascimento, H. Carvalho, Andrés Navarrete Castro, Arlindo César Matias Pereira, Carlos Eduardo Winter, I. D. S. Sena, Luiz Fernando Moreira, J. C. T. Carvalho","doi":"10.3390/jal3040022","DOIUrl":null,"url":null,"abstract":"Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.","PeriodicalId":73588,"journal":{"name":"Journal of ageing and longevity","volume":"81 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans\",\"authors\":\"Ester Lopes de Melo, Bruno Augusto Machado Tavares, Nayara Nílcia Dias Colares, Aline Lopes do Nascimento, H. Carvalho, Andrés Navarrete Castro, Arlindo César Matias Pereira, Carlos Eduardo Winter, I. D. S. Sena, Luiz Fernando Moreira, J. C. T. Carvalho\",\"doi\":\"10.3390/jal3040022\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.\",\"PeriodicalId\":73588,\"journal\":{\"name\":\"Journal of ageing and longevity\",\"volume\":\"81 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of ageing and longevity\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/jal3040022\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of ageing and longevity","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/jal3040022","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans
Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.