Euterpe oleracea、Bixa orellana、Myciaria dubia 和 Astrocaryum aculeatum(Terasen® Nutraceutical)的结合可延长秀丽隐杆线虫的寿命

Ester Lopes de Melo, Bruno Augusto Machado Tavares, Nayara Nílcia Dias Colares, Aline Lopes do Nascimento, H. Carvalho, Andrés Navarrete Castro, Arlindo César Matias Pereira, Carlos Eduardo Winter, I. D. S. Sena, Luiz Fernando Moreira, J. C. T. Carvalho
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引用次数: 0

摘要

衰老是一个复杂的过程,与组织退化和老年相关疾病风险增加有关。本研究旨在评估 Terasen® 对 elegans(秀丽隐杆线虫)寿命的影响,Terasen® 是一种营养保健品,含有 Euterpe oleracea、Myrciaria dubia 的标准化提取物以及 Bixa orellana 和 Astrocaryum aculeatum 的纯化油。研究结果表明,Terasen® 在体外具有显著的自由基清除作用,能减少秀丽隐杆线虫的摄食行为,但不影响动物的最终体型,能以浓度依赖性方式增加产卵量,但与对照组相比,后代总数有所减少,并能延长中位寿命和最长寿命。这些研究结果表明,Terasen® 可提高秀丽隐杆线虫的寿命,值得进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of Euterpe oleracea, Bixa orellana, Myciaria dubia, and Astrocaryum aculeatum (the Terasen® Nutraceutical) Increases the Lifespan of Caenorhabditis elegans
Aging is a complex process associated with tissue degeneration and an increased risk of age-related diseases. This study aimed to evaluate the impact of Terasen®, a nutraceutical containing standardized extracts of Euterpe oleracea, Myrciaria dubia, and purified oil of Bixa orellana and Astrocaryum aculeatum on the lifespan of Caenorhabditis elegans. The findings demonstrated that Terasen® exhibited significant radical scavenging in vitro, decreased the feeding behavior of C. elegans without affecting the animals’ final size, increased the eggs laid in a concentration-dependent fashion, although the total progeny was reduced compared to the control, and increased the median and maximum lifespan. These findings suggest that Terasen® may improve the lifespan in C. elegans, warranting further investigation.
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