局部晚期直肠乙状结肠交界癌中的塔克次氏心肌病:病例报告

Q4 Medicine
I. E. Alekseev, N. L. Lysovolenko, E. V. Gavrilyuk, V. V. Khvostovoi, N. V. Lazareva, А. M. Bykanova, E. N. Grebenkin, I. V. Stanoevich
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引用次数: 0

摘要

背景:与普通人群相比,癌症患者中发生塔克次博心肌病(takotsubo cardiomyopathy,tcm)的频率更高。癌症患者诱发 Tcm 的因素不仅包括癌症本身的炎症状态,还包括癌症诊断带来的巨大精神压力以及侵入性诊断和治疗过程带来的身体压力。我们描述了一例经组织学证实患有直肠乙状结肠交界癌(cT4bcN2M0)并发急性肠梗阻的 54 岁女性病例。术后早期,血压突然下降,心电图出现 t 波倒置和 Qt 间期延长,左心室收缩力下降,超声心动图(ecHo)出现室壁运动异常,心肌损伤的生物标志物增加,最初被认为是急性冠状动脉综合征,但随后根据冠状动脉造影的结果排除了这一病例,因为造影并未发现冠状动脉阻塞。考虑到变化的快速和完全反向动态,排除了无冠状动脉阻塞的急性心肌梗死和急性心肌炎。结论:本病例报告表明,癌症可能是诱发拓扑型心肌病的导火索;因此,在癌症治疗期间对癌症患者的心脏状况进行评估并及时发现心脏并发症极为重要,其目的在于提高这类患者的总体生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Takotsubo cardiomyopathy in locally advanced rectosigmoid junction cancer: a case report
Background. takotsubo cardiomyopathy (tcm) occurs more frequently in cancer patients than in the general population. The triggers for tcm in cancer patients include not only the inflammatory state of the cancer itself, but also the significant emotional stress of a cancer diagnosis and the physical stress associated with invasive diagnostic and treatment procedures.Case presentation. We describe the case of a 54-yearold woman with histologically verified rectosigmoid junction cancer (cT4bcN2M0) complicated by acute intestinal obstruction. In the early postoperative period, a sudden drop in blood pressure, t-wave inversion and Qt-interval prolongation on ecg, decrease in the left ventricle contractility and presence of wall motion abnormalities on echocardiography (ecHo), as well as an increase in biomarkers of myocardial damage were initially regarded as acute coronary syndrome, which was subsequently excluded according to the findings of coronary angiography, which did not reveal coronary artery obstruction. taking into account the rapid and complete inverse dynamics of changes, acute myocardial infarction without coronary artery obstruction and acute myocarditis were excluded. Ultimately, the diagnosis of takotsubo cardiomyopathy was established.Conclusion. this case report indicates that cancer can be a trigger for the development of tcm; therefore, the assessment of cardiological status and timely detection of cardiac complications in cancer patients during cancer treatment is extremely important and is aimed at increasing the overall survival in this category of patients.
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来源期刊
Siberian journal of oncology
Siberian journal of oncology Medicine-Oncology
CiteScore
0.40
自引率
0.00%
发文量
117
审稿时长
8 weeks
期刊介绍: The main objectives of the journal are: -to promote the establishment of Russia’s leading worldwide positions in the field of experimental and clinical oncology- to create the international discussion platform intended to cover all aspects of basic and clinical cancer research, including carcinogenesis, molecular biology, epidemiology, cancer prevention, diagnosis and multimodality treatment (surgery, chemotherapy, radiation therapy, hormone therapy), anesthetic management, medical and social rehabilitation, palliative care as well as the improvement of life quality of cancer patients- to encourage promising young scientists to be actively involved in cancer research programs- to provide a platform for researches and doctors all over the world to promote, share, and discuss various new issues and developments in cancer related problems. (to create a communication platform for the expansion of cooperation between Russian and foreign professional associations).- to provide the information about the latest worldwide achievements in different fields of oncology The most important tasks of the journal are: -to encourage scientists to publish their research results- to offer a forum for active discussion on topics of major interest - to invite the most prominent Russian and foreign authors to share their latest research findings with cancer research community- to promote the exchange of research information, clinical experience, current trends and the recent developments in the field of oncology as well as to review interesting cases encountered by colleagues all over the world- to expand the editorial board and reviewers with the involvement of well-known Russian and foreign experts- to provide open access to full text articles- to include the journal into the international database- to increase the journal’s impact factor- to promote the journal to the International and Russian markets
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