{"title":"研究 \"Ortof-S \"片剂的抗炎活性","authors":"Yunusova Malikakhon Saidhabibovna, Allayeva Munira Jurabayevna, Yunusova Kholida Mannanovna, Jaloliddinova Muattar Shukhrat Qizi, Anvarova Farangiz Jamshid Qizi","doi":"10.15379/ijmst.v10i2.3172","DOIUrl":null,"url":null,"abstract":"The results of the study of pharmacological studies of the recommended tablets “Ortof-S” by the method “carrageenan paw edema in rats” are presented. The first stage of the study, the anti-inflammatory effect of the compared drugs “Ortof-S”, manufactured by LLC “SAMO”, Uzbekistan and “Ketaneym”, manufactured by “NEOUNIVERSE LLP”, London, UK, was studied by the method of “carrageenan paw edema in rats” anti-inflammatory activity bioavailability is to determine the solubility or release time of the drug from the medicinal forms. It was found that the solubility test characterizes the biological availability of the drug in the first approximation, since in practice there is a very frequent correlation between the rate of dissolution and absorption. The solubility, foreign impurities and the quantitative content of active substances were studied.","PeriodicalId":301862,"journal":{"name":"International Journal of Membrane Science and Technology","volume":"73 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"STUDY OF ANTI-INFLAMMATORY ACTIVITY OF “ORTOF-S” TABLETS\",\"authors\":\"Yunusova Malikakhon Saidhabibovna, Allayeva Munira Jurabayevna, Yunusova Kholida Mannanovna, Jaloliddinova Muattar Shukhrat Qizi, Anvarova Farangiz Jamshid Qizi\",\"doi\":\"10.15379/ijmst.v10i2.3172\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The results of the study of pharmacological studies of the recommended tablets “Ortof-S” by the method “carrageenan paw edema in rats” are presented. The first stage of the study, the anti-inflammatory effect of the compared drugs “Ortof-S”, manufactured by LLC “SAMO”, Uzbekistan and “Ketaneym”, manufactured by “NEOUNIVERSE LLP”, London, UK, was studied by the method of “carrageenan paw edema in rats” anti-inflammatory activity bioavailability is to determine the solubility or release time of the drug from the medicinal forms. It was found that the solubility test characterizes the biological availability of the drug in the first approximation, since in practice there is a very frequent correlation between the rate of dissolution and absorption. The solubility, foreign impurities and the quantitative content of active substances were studied.\",\"PeriodicalId\":301862,\"journal\":{\"name\":\"International Journal of Membrane Science and Technology\",\"volume\":\"73 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Membrane Science and Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15379/ijmst.v10i2.3172\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Membrane Science and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15379/ijmst.v10i2.3172","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
STUDY OF ANTI-INFLAMMATORY ACTIVITY OF “ORTOF-S” TABLETS
The results of the study of pharmacological studies of the recommended tablets “Ortof-S” by the method “carrageenan paw edema in rats” are presented. The first stage of the study, the anti-inflammatory effect of the compared drugs “Ortof-S”, manufactured by LLC “SAMO”, Uzbekistan and “Ketaneym”, manufactured by “NEOUNIVERSE LLP”, London, UK, was studied by the method of “carrageenan paw edema in rats” anti-inflammatory activity bioavailability is to determine the solubility or release time of the drug from the medicinal forms. It was found that the solubility test characterizes the biological availability of the drug in the first approximation, since in practice there is a very frequent correlation between the rate of dissolution and absorption. The solubility, foreign impurities and the quantitative content of active substances were studied.
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