The effect of L. reuteri on Nonspecific Resistance and Hematological Parameters of Laboratory Animals

Probiotics are microbial preparations, which have a positive effect on the composition of the intestinal microflora and the immune system of animals. These preparations are widely used for correcting and preventing violations of the microflora of the gastrointestinal tract. Lactobacilli play a special role in the formation of normal microflora. They exhibit a pronounced antagonistic activity against pathogenic and opportunistic microorganisms, as well as possess a number of other positive effects. This study is aimed at determining the effect of new probiotic strains of L. reuteri on the indicators of nonspecific resistance, hematological and biochemical parameters of laboratory rabbits. The studied strains were found to have a pronounced positive effect on the indicators of nonspecific resistance. Thus, compared to the control, the indicators of phagocytic activity and bactericidal activity in the experimental group were by 22% and 32% higher, respectively. The content of hemoglobin, erythrocytes and total protein in the blood serum also increased.