通过体外和体内方法研究药物 "BISKOR "的生物制药特性

Yunusova Kholida Mannanovna, Jaloliddinova Muattar Shukhrat Qizi, Ilkhamova Nargiza Bakhtiyarovna, Anvarova Farangiz Jamshid Qizi
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引用次数: 0

摘要

通过体外和体内方法对推荐药片 "Biskor "的生物药学特性进行研究的结果。生物药效率研究的第一步是确定药物从剂型中的溶解度或释放时间。已经证实,溶解度测试是药物生物利用度的第一近似特征,因为在实践中,溶解速率和吸收速率之间经常存在相关性。对溶解度、外来杂质和活性物质的定量含量进行了研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
STUDYING THE BIOPHARMACEUTICAL PROPERTIES OF THE DRUG “BISKOR” BY METHODS IN VITRO AND IN VIVO
The results of the study of the biopharmaceutical properties of the recommended tablets “Biskor” by methods in vitro and in vivo. The first step in a bioavailability study is to determine the solubility or release time of the drug from the dosage form. It has been established that the solubility test in the first approximation characterizes the bioavailability of the drug, since in practice there is a very frequent correlation between the rate of dissolution and absorption. The solubility, foreign impurities and the quantitative content of active substances were studied.
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