{"title":"SPINK1 研究简评","authors":"Latai Ga","doi":"10.54097/ijbls.v4i1.14","DOIUrl":null,"url":null,"abstract":"SPINK1, a trypsin inhibitor secreted by the pancreas, is closely associated with the development of pancreatitis. Additionally, SPINK1 exhibits multiple biological functions, acting as a trypsin inhibitor, a growth factor-like protein, and a negative regulator of autophagy. This paper reviews the role of the SPINK1 gene and its variants in pancreatitis development, its expression as TATI in cancer, and its role in oncogenesis.","PeriodicalId":507854,"journal":{"name":"International Journal of Biology and Life Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Brief Review of SPINK1 Studies\",\"authors\":\"Latai Ga\",\"doi\":\"10.54097/ijbls.v4i1.14\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"SPINK1, a trypsin inhibitor secreted by the pancreas, is closely associated with the development of pancreatitis. Additionally, SPINK1 exhibits multiple biological functions, acting as a trypsin inhibitor, a growth factor-like protein, and a negative regulator of autophagy. This paper reviews the role of the SPINK1 gene and its variants in pancreatitis development, its expression as TATI in cancer, and its role in oncogenesis.\",\"PeriodicalId\":507854,\"journal\":{\"name\":\"International Journal of Biology and Life Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Biology and Life Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.54097/ijbls.v4i1.14\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Biology and Life Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54097/ijbls.v4i1.14","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SPINK1, a trypsin inhibitor secreted by the pancreas, is closely associated with the development of pancreatitis. Additionally, SPINK1 exhibits multiple biological functions, acting as a trypsin inhibitor, a growth factor-like protein, and a negative regulator of autophagy. This paper reviews the role of the SPINK1 gene and its variants in pancreatitis development, its expression as TATI in cancer, and its role in oncogenesis.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
