研究冷冻切片对乳腺癌病理诊断的影响

Ying Shen
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摘要

目的分析冰冻切片病理学在乳腺癌诊断中的诊断价值。方法随机选取 2021 年 7 月至 2023 年 2 月期间接受治疗的 50 例乳腺肿瘤患者作为样本。同时进行石蜡切片和冰冻切片诊断。石蜡切片结果作为评估冰冻切片检查价值的金标准。结果在冰冻切片诊断中,确诊 48 例(96.00%),误诊 1 例(2.00%),延误 1 例(2.00%)。在确诊患者中,45 例(90.00%)完全一致,3 例(6.00%)基本一致。冰冻切片的诊断率为 96.00%,而石蜡切片的诊断率为 100.00%(P > 0.05)。冰冻切片的诊断时间(35.25 ± 2.11 分钟)明显短于石蜡切片(6911.36 ± 58.36 分钟;P < 0.05)。结论冷冻切片诊断速度快,诊断准确率相对较高。它能指导医生决定是否进行保乳治疗,并帮助选择合适的手术方法。这有利于避免不必要的医疗干预,减少乳腺癌患者对二次手术的需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Examining the Pathological Diagnostic Impact of Frozen Sections in Breast Cancer
Objective: To analyze the diagnostic value of frozen section pathology in the diagnosis of breast cancer. Methods: A total of 50 patients with breast tumors treated between July 2021 and February 2023 were randomly selected as samples. Both paraffin section and frozen section diagnoses were conducted. The paraffin section results served as the gold standard for evaluating the value of frozen section examination. Results: Among the frozen section diagnoses, 48 cases (96.00%) were confirmed, 1 case was misdiagnosed (2.00%), and 1 case was delayed (2.00%). Among the confirmed patients, 45 cases (90.00%) were entirely consistent, and 3 cases (6.00%) were basically consistent. The diagnostic rate of the frozen section was 96.00%, compared with 100.00% for the paraffin section (P > 0.05). The diagnostic time of the frozen section (35.25 ± 2.11 min) was significantly shorter than that for the paraffin section (6911.36 ± 58.36 min; P < 0.05). Conclusion: Frozen section diagnosis is rapid and demonstrates relatively high diagnostic accuracy. It can guide doctors in determining whether to pursue breast-conserving treatment and aid in selecting appropriate surgical methods. This is beneficial for preventing unnecessary medical interventions and reducing the need for secondary surgeries in breast cancer patients.
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