为可持续化妆品开发植物配方

IF 3.4 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
L. Lima, Karina Bispo-dos-Santos, Ingrid Mayara Cavalcante Trevisan, Catarina Rapôso, P. Velho, E. Bagatin, Rodrigo Alvarenga Rezende, Jorge Vicente Lopes da Silva, Gislaine Ricci Leonardi
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引用次数: 0

摘要

由于化妆品配方的极简主义、水的合理使用以及防腐剂、着色剂、表面活性剂和人工香料等化学添加剂的减少,人们对清洁美容的兴趣日益高涨。绿色成分有助于开发性能先进、对人类健康和环境影响较小的可持续配方。目前,电纺丝技术作为一种简单的一步法生产工艺,可在温和的温度条件下生产纳米结构的化妆品。本研究的重点是利用米糠油(RBO)制造可持续的纳米结构化妆品,用于潜在的化妆品和保健应用。研究人员利用乙基纤维素和米糠油(RBO)开发了四种可持续配方,以优化纳米结构化妆品的制作。由于乙醇和聚乙烯吡咯烷酮具有生物相容性和生物降解性,我们选择它们来组成可持续配方。我们研究了四种不同浓度的米糠油的形态、封装效率、生物降解性和细胞毒性。纳米结构化妆品具有仿生物表面、高 RBO 封装能力、模拟生理条件下的低质量损失和无细胞毒性。因此,这种极简的可持续配方不含任何有毒溶剂和不兼容的有害辅料,采用温和的制造工艺制成纳米结构,并获得了较高的 RBO 包封能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Developing Botanical Formulations for Sustainable Cosmetics
Interest in clean beauty is rising due to minimalism in the formulation of cosmetics, rational use of water, and fewer chemical additives like preservatives, colorants, surfactants, and artificial fragrances. Green ingredients lead to the development of sustainable formulations with advanced performance and are less aggressive to human health and the environment. Currently, the electrospinning technique is used as a simple one-step manufacturing process to produce nanostructured cosmetics under mild temperature conditions. This study focuses on the utilization of rice bran oil (RBO) in the creation of sustainable nanostructured cosmetics for potential cosmetic and well-being applications. Four sustainable formulations were developed to optimize the creation of nanostructured cosmetics using ethyl cellulose and rice bran oil (RBO). Ethanol absolute and polyvinyl pyrrolidone have been chosen to compose the sustainable formulation due to their biocompatibility and biodegradability. We studied four different RBO concentrations regarding morphology, encapsulation efficiency, biodegradability, and cytotoxicity. Nanostructured cosmetics present biomimetic surfaces, high RBO encapsulation ability, low mass loss at simulated physiologic conditions, and non-cytotoxicity. Therefore, the minimalist sustainable formulation does not contain any toxic solvents and incompatible harmful excipients, was nanostructured using a mild manufacturing process, and obtained high RBO entrapment.
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来源期刊
Cosmetics
Cosmetics Medicine-Surgery
CiteScore
5.20
自引率
12.10%
发文量
108
审稿时长
8 weeks
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