Ocular myasthenia gravis and blepharospasm: similarities and differences

The ocular myasthenia gravis and blepharospasm are two diseases that can involve the periocular area in the pathological process. In both diseases, patients complain of closing their eyes. In both cases may be observed frequent blinking, worsening of symptoms in bright light. Blepharospasm associated with a violent contraction of the circular muscle of the eye, and myasthenia gravis related pathology of the neuromuscular synapse of the extraocular muscles. The article presents the clinical features of both diseases and diagnostic maneuvers that help in determining the diagnosis of the ocular myasthenia gravis and blepharospasm in clinically difficult cases.