随着时间推移血管狭窄程度加重对血液动力学的影响

Q2 Agricultural and Biological Sciences
Pushpa Nidhi Gautam, C. Pokharel, G. R. Phaijoo, Parameshwari Kattel, J. Kafle
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引用次数: 0

摘要

动脉内壁形成的硬层会使血液流动不畅,并会因供血异常而损害心血管系统。随着时间的推移,沉积层会越来越厚,问题也会越来越严重。通过将血液作为非牛顿流体,研究了动脉狭窄增加对流动特性的影响。为了解决狭窄程度随时间增加而产生的影响,在狭窄的几何形状中加入了一个非维度时间项,并应用该时间项推导出速度曲线、容积流量和压降等流动参数。最大和最小剪应力比以及压降比也是通过该术语计算得出的。对所得结果进行分析,以显示随着时间的推移,狭窄程度的增加对这些流动参数的影响。在分析结果时,将容积流量、压降及其比率、剪应力比率与狭窄处厚度和正常动脉半径的比率进行了比较。结果发现,随着时间的推移,容积流量逐渐减小,压降及其比值逐渐增大,剪应力比值逐渐减小。结果表明,加入时间项来理解狭窄程度随时间增加对血流参数的影响是合适的。本文旨在纠正假设狭窄为对称形状时所产生的弊端。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of increasing stenosis over time on hemodynamics
A hard layer, that develops in the inner wall of an artery, makes the blood flow difficult and it can harm the cardiovascular system because of the abnormality in blood supply. The problem becomes worse when the layer gets thicker due to increased deposition over time. The effect of increasing stenosis on flow characteristics in an artery is studied by taking blood as a non-Newtonian fluid. To address the effect of increasing stenosis over time, a non-dimensional temporal term is included in the geometry of stenosis and is applied to derive the flow parameters like velocity profile, volumetric flow rate and pressure drop. The maximum and minimum shear stress ratio and pressure drop ratio are also calculated using the term. The results obtained are analyzed to show the effect of increasing stenosis over time on these flow parameters. Volumetric flow rate, pressure drop and its ratio, and shear stress ratio are compared with the ratio of the thickness of the stenosis and normal artery radius while analyzing the results. It is found that the volumetric flow rate decreases with time, pressure drop and its ratio increases with time, and the shear stress ratio decreases as the time elapses. The result shows that it is appropriate to include the temporal term to understand the effect of increasing stenosis over time on blood flow parameters. The aim of this article is to correct the drawback that evolves while supposing the symmetric shape of the stenosis.
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来源期刊
Biomath
Biomath Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)
CiteScore
2.20
自引率
0.00%
发文量
6
审稿时长
20 weeks
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