达卡一家三甲医院收治的五岁以下儿童登革热临床概况和治疗结果

Tasnima Ahmed, J. Nahar, F. Mohsin, N. Islam, Sabrina Jashim
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引用次数: 0

摘要

背景:登革热已成为孟加拉国的一个主要公共卫生问题,其感染率和严重程度都在逐渐上升。最易感染的人群是儿童,尤其是 5 岁以下的儿童。然而,有关该年龄组登革热的数据却很有限。本研究的目的是了解 5 岁以下儿童登革热(DF)的临床和实验室概况及其结果。研究方法这项横断面观察研究于 2023 年 5 月至 2023 年 9 月在 BIRDEM 综合医院儿科进行。共有 189 例登革热确诊病例参与研究。研究记录并分析了他们的临床概况和实验室检查结果,包括血红蛋白(Hb%)、血细胞比容(Hct)、白细胞总数(TC)、血小板计数(PC)、血清丙氨酸氨基转移酶(S. ALT)、血清天门冬氨酸氨基转移酶(S. AST)、凝血酶原时间(PT)、国际标准化比值(INR)、活化部分凝血活酶时间(aPTT)、血清钙和血清钠水平。结果189 名儿童中有 57 名(30.1%)是婴儿,132 名(69.8%)患者年龄在 1 至 5 岁之间。根据登革热的严重程度,98 名儿童(51.8%)为典型登革热,65 名儿童(34.3%)和 14 名儿童(7.4%)分别出现登革休克综合征(DSS)和登革出血热(DHF)。所有患儿均出现发热,其他常见症状包括呕吐(34.9%)、咳嗽(25.9%)、脱水(26.9%)、胸腔积液(34.3%)、腹水(23.2%)和皮疹(18.5%)。41.1%的病例出现休克。16.4%、9.5%、2.6%和11.6%的病例出现烦躁不安、嗜睡、意识改变和抽搐等警示症状。所有患儿均好转出院。结论在这项研究中,大多数儿童的登革热症状都很典型。登革休克综合征和登革出血热的发病率低于 10%。无论采用哪种治疗方法,疗效都很好。及早向医院报告显得非常重要。J Bangladesh Coll Phys Surg 2023; 41: 25-28
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Profile and outcome of Dengue Fever in Under 5 Children Admitted at a Tertiary Care Hospital, Dhaka
Background: Dengue has become a major public health problem in Bangladesh with gradually increasing infectivity and severity. Most vulnerable population are children especially children below 5 years of age. However, data regarding dengue among this age group is limited. The objectives of this study were to see the clinical and laboratory profile of dengue fever (DF) in children below 5 years of age and their outcome. Methods: This cross – sectional observational study was carried out in the department of Paediatrics, BIRDEM General Hospital from May 2023 to September 2023. One hundred eighty nine confirmed dengue cases were enrolled in the study. Their clinical profile and laboratory findings including haemoglobin (Hb%), haematocrit (Hct), total count of white blood cells (TC), platelet count (PC), serum alanine aminotransferase (S. ALT), serum aspartate aminotransaminase (S. AST), prothrombin time (PT), international normalized ratio (INR), activated partial thromboplastin time (aPTT), serum calcium and serum sodium level were documented and analyzed. Results: Among 189 children 57(30.1%) were infants and 132(69.8%) patients were aged 1 to 5 years. Depending upon the severity of dengue 98(51.8%) were classical dengue fever, 65(34.3%) and 14(7.4%) presented with dengue shock syndrome (DSS) and dengue heamorrhagic fever (DHF) respectively. Fever was present in all children, other common features were vomiting (34.9%), cough (25.9%), dehydration (26.9%), pleural effusion (34.3%), ascites (23.2%) and skin rash (18.5%). Shock were present in 41.1% cases. Warning signs like restlessness, lethargy, altered level of consciousness, convulsion was present in 16.4%, 9.5%, 2.6% and 11.6% respectively. All the children were improved and discharged. Conclusion: In this study dengue presented classically in most of the children. Dengue shock syndrome and dengue haemorrhagic fever were below 10%. The outcome was excellent with no modality. Early reporting to hospital appeared important. J Bangladesh Coll Phys Surg 2023; 41: 25-28
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