Tatevik Aloyan, Zaruhi G. Kalikyan, Sona Harutyunyan, Alexandra Zakaryan, Mariam Movsisyan, Lusntag Ktsoyan, Ovanes Karslyan, Armine V. Hakobyan
{"title":"史蒂文斯-约翰逊综合征和中毒性表皮坏死症：系列病例和简要文献综述","authors":"Tatevik Aloyan, Zaruhi G. Kalikyan, Sona Harutyunyan, Alexandra Zakaryan, Mariam Movsisyan, Lusntag Ktsoyan, Ovanes Karslyan, Armine V. Hakobyan","doi":"10.54235/27382737-2023.v3.1-67","DOIUrl":null,"url":null,"abstract":"Stevens-Johnson syndrome (SJS) and toxic epi- dermal necrolysis (TEN) are rare forms of delayed-type drug hypersensitivity reactions (DHRs) with extensive skin necrosis and exfoliation. Drugs are the main cause of SJS and TEN in both adults and children. The most common medications are allopurinol, aromatic antiepileptics and sulfonamides with seasonal, geographical and ethnic variations. The purpose of this paper is to present the cases of SJS/TEN which were successfully treated during the year of 2021 in our department and to provide a brief literature review.","PeriodicalId":117806,"journal":{"name":"Armenian Journal of Health & Medical Sciences","volume":"29 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Stevens-Johnson syndrome and toxic epidermal necrolysis: case series and brief literature review\",\"authors\":\"Tatevik Aloyan, Zaruhi G. Kalikyan, Sona Harutyunyan, Alexandra Zakaryan, Mariam Movsisyan, Lusntag Ktsoyan, Ovanes Karslyan, Armine V. Hakobyan\",\"doi\":\"10.54235/27382737-2023.v3.1-67\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Stevens-Johnson syndrome (SJS) and toxic epi- dermal necrolysis (TEN) are rare forms of delayed-type drug hypersensitivity reactions (DHRs) with extensive skin necrosis and exfoliation. Drugs are the main cause of SJS and TEN in both adults and children. The most common medications are allopurinol, aromatic antiepileptics and sulfonamides with seasonal, geographical and ethnic variations. The purpose of this paper is to present the cases of SJS/TEN which were successfully treated during the year of 2021 in our department and to provide a brief literature review.\",\"PeriodicalId\":117806,\"journal\":{\"name\":\"Armenian Journal of Health & Medical Sciences\",\"volume\":\"29 8\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-11-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Armenian Journal of Health & Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.54235/27382737-2023.v3.1-67\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Armenian Journal of Health & Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.54235/27382737-2023.v3.1-67","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
史蒂文斯-约翰逊综合征（SJS）和中毒性表皮坏死（TEN）是一种罕见的迟发型药物超敏反应（DHRs），伴有大面积皮肤坏死和脱皮。药物是导致成人和儿童 SJS 和 TEN 的主要原因。最常见的药物是别嘌呤醇、芳香族抗癫痫药和磺胺类药物，但有季节、地域和种族差异。本文旨在介绍我科 2021 年成功治疗的 SJS/TEN 病例，并提供简要的文献综述。
Stevens-Johnson syndrome and toxic epidermal necrolysis: case series and brief literature review
Stevens-Johnson syndrome (SJS) and toxic epi- dermal necrolysis (TEN) are rare forms of delayed-type drug hypersensitivity reactions (DHRs) with extensive skin necrosis and exfoliation. Drugs are the main cause of SJS and TEN in both adults and children. The most common medications are allopurinol, aromatic antiepileptics and sulfonamides with seasonal, geographical and ethnic variations. The purpose of this paper is to present the cases of SJS/TEN which were successfully treated during the year of 2021 in our department and to provide a brief literature review.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
