利用世界卫生组织的 "获取、观察、储备"(AWaRe)分类法,生成人类和动物健康领域抗生素使用的证据:印度浦那农村地区的探索性试点研究

Q2 Veterinary
A. Kudale, Sakshi Shantanu Hiralkar, Pravin Arun Sawant, Yogita Purushottam Hulsurkar, Nikhil Rajkumar Fatate, Priya Padmakar Waghmare, A. Randive, Mugdha Sharad Phutane, Prashant Pawar, Prashant Mhase
{"title":"利用世界卫生组织的 \"获取、观察、储备\"(AWaRe)分类法,生成人类和动物健康领域抗生素使用的证据:印度浦那农村地区的探索性试点研究","authors":"A. Kudale, Sakshi Shantanu Hiralkar, Pravin Arun Sawant, Yogita Purushottam Hulsurkar, Nikhil Rajkumar Fatate, Priya Padmakar Waghmare, A. Randive, Mugdha Sharad Phutane, Prashant Pawar, Prashant Mhase","doi":"10.14202/ijoh.2023.166-171","DOIUrl":null,"url":null,"abstract":"Background and Aim: Human antibiotic formulations in animal feed for therapeutic and non-therapeutic purposes have contributed to antimicrobial resistance worldwide; however, little evidence is available in low- and middle-income countries. We aimed to generate evidence of antibiotic use across the human and animal health sectors by investigating the overlap in antibiotic use in community settings in rural blocks of Pune District, India, following the World Health Organization’s (WHO) Access, Watch, Reserve (AWaRe) classification. Materials and Methods: An exploratory pilot study using a cross-sectional design in two randomly selected rural blocks of the Pune district included 138 interviews with general physicians (GPs, n = 62), pharmacists (n = 60), and veterinary practitioners (n = 16) using semi-structured interview schedules and the WHO AWaRe classification. IBM-Statistical Package for the Social Sciences, Version 21.0 software was used for descriptive statistics and to calculate the proportions of the different antibiotic groups. The WHO AWaRe classification was used to describe antibiotic use by the study participants and to assess the overlap in antibiotic use. Results: Our study provides evidence of an overlap in human and animal antibiotic use in rural community settings across the human and animal health sectors. Amoxicillin (access group), penicillin (access group), and ofloxacin (watch group) were used in both human and animal health. Amoxicillin and penicillin were used to treat common bacterial infections, ofloxacin was used to treat skin infections in humans and animals, and ofloxacin was used to treat pneumonia in animals and urinary bladder infections in humans. In contrast, azithromycin (watch group), cefixime (watch group), and amoxicillin (Access Group), with or without other antibiotics, were the most commonly used antibiotics by GPs in humans. Conclusion: We confirmed the overlap in antibiotic use across the human and animal health sectors in rural community settings, suggesting the need for interventions following the One Health approach. Further, research is required to assess the patterns of this overlap, as well as behavior, knowledge, and potential solutions to help avoid this overlap and prevent the rampant use of antibiotics in the animal and human health sectors in rural community settings. Keywords: antimicrobial resistance, antibiotics use, overlap, rural India, WHO AWaRe.","PeriodicalId":37300,"journal":{"name":"International Journal of One Health","volume":"89 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Generating evidence on antibiotic use across human and animal health sectors using the World Health Organization’s Access, Watch, Reserve (AWaRe) classification: Exploratory pilot study in rural Pune, India\",\"authors\":\"A. Kudale, Sakshi Shantanu Hiralkar, Pravin Arun Sawant, Yogita Purushottam Hulsurkar, Nikhil Rajkumar Fatate, Priya Padmakar Waghmare, A. Randive, Mugdha Sharad Phutane, Prashant Pawar, Prashant Mhase\",\"doi\":\"10.14202/ijoh.2023.166-171\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background and Aim: Human antibiotic formulations in animal feed for therapeutic and non-therapeutic purposes have contributed to antimicrobial resistance worldwide; however, little evidence is available in low- and middle-income countries. We aimed to generate evidence of antibiotic use across the human and animal health sectors by investigating the overlap in antibiotic use in community settings in rural blocks of Pune District, India, following the World Health Organization’s (WHO) Access, Watch, Reserve (AWaRe) classification. Materials and Methods: An exploratory pilot study using a cross-sectional design in two randomly selected rural blocks of the Pune district included 138 interviews with general physicians (GPs, n = 62), pharmacists (n = 60), and veterinary practitioners (n = 16) using semi-structured interview schedules and the WHO AWaRe classification. IBM-Statistical Package for the Social Sciences, Version 21.0 software was used for descriptive statistics and to calculate the proportions of the different antibiotic groups. The WHO AWaRe classification was used to describe antibiotic use by the study participants and to assess the overlap in antibiotic use. Results: Our study provides evidence of an overlap in human and animal antibiotic use in rural community settings across the human and animal health sectors. Amoxicillin (access group), penicillin (access group), and ofloxacin (watch group) were used in both human and animal health. Amoxicillin and penicillin were used to treat common bacterial infections, ofloxacin was used to treat skin infections in humans and animals, and ofloxacin was used to treat pneumonia in animals and urinary bladder infections in humans. In contrast, azithromycin (watch group), cefixime (watch group), and amoxicillin (Access Group), with or without other antibiotics, were the most commonly used antibiotics by GPs in humans. Conclusion: We confirmed the overlap in antibiotic use across the human and animal health sectors in rural community settings, suggesting the need for interventions following the One Health approach. Further, research is required to assess the patterns of this overlap, as well as behavior, knowledge, and potential solutions to help avoid this overlap and prevent the rampant use of antibiotics in the animal and human health sectors in rural community settings. Keywords: antimicrobial resistance, antibiotics use, overlap, rural India, WHO AWaRe.\",\"PeriodicalId\":37300,\"journal\":{\"name\":\"International Journal of One Health\",\"volume\":\"89 4\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of One Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.14202/ijoh.2023.166-171\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Veterinary\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of One Health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14202/ijoh.2023.166-171","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Veterinary","Score":null,"Total":0}
引用次数: 0

摘要

背景与目的:在动物饲料中添加用于治疗和非治疗目的的人类抗生素制剂已在全球范围内导致了抗菌药耐药性的产生;然而,在中低收入国家却鲜有相关证据。我们的目的是根据世界卫生组织(WHO)的 "获取、观察、储备"(AWaRe)分类法,调查印度浦那区农村社区抗生素使用的重叠情况,从而为人类和动物健康领域的抗生素使用提供证据。 材料与方法:一项探索性试点研究采用横断面设计,在普纳区随机选取的两个农村街区进行了 138 次访谈,访谈对象包括全科医生(62 人)、药剂师(60 人)和兽医(16 人),访谈采用半结构化访谈表和世界卫生组织 AWaRe 分类法。使用 IBM 社会科学统计软件包 21.0 版进行描述性统计,并计算不同抗生素组的比例。世界卫生组织 AWaRe 分类用于描述研究参与者使用抗生素的情况,并评估抗生素使用的重叠情况。 研究结果我们的研究证明,在农村社区环境中,人类和动物抗生素的使用存在重叠现象。阿莫西林(接触组)、青霉素(接触组)和氧氟沙星(观察组)被用于人类和动物健康。阿莫西林和青霉素用于治疗常见的细菌感染,氧氟沙星用于治疗人类和动物的皮肤感染,氧氟沙星用于治疗动物的肺炎和人类的膀胱感染。相比之下,阿奇霉素(观察组)、头孢克肟(观察组)和阿莫西林(准入组),无论是否使用其他抗生素,都是全科医生在人类中最常用的抗生素。 结论我们证实,在农村社区环境中,人类和动物健康领域的抗生素使用存在重叠,这表明有必要采取 "统一健康 "方法进行干预。此外,还需要开展研究来评估这种重叠的模式,以及行为、知识和潜在的解决方案,以帮助避免这种重叠,防止抗生素在农村社区环境中的动物和人类健康领域的肆意使用。 关键词:抗菌药耐药性、抗生素使用、重叠、印度农村、WHO AWaRe。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Generating evidence on antibiotic use across human and animal health sectors using the World Health Organization’s Access, Watch, Reserve (AWaRe) classification: Exploratory pilot study in rural Pune, India
Background and Aim: Human antibiotic formulations in animal feed for therapeutic and non-therapeutic purposes have contributed to antimicrobial resistance worldwide; however, little evidence is available in low- and middle-income countries. We aimed to generate evidence of antibiotic use across the human and animal health sectors by investigating the overlap in antibiotic use in community settings in rural blocks of Pune District, India, following the World Health Organization’s (WHO) Access, Watch, Reserve (AWaRe) classification. Materials and Methods: An exploratory pilot study using a cross-sectional design in two randomly selected rural blocks of the Pune district included 138 interviews with general physicians (GPs, n = 62), pharmacists (n = 60), and veterinary practitioners (n = 16) using semi-structured interview schedules and the WHO AWaRe classification. IBM-Statistical Package for the Social Sciences, Version 21.0 software was used for descriptive statistics and to calculate the proportions of the different antibiotic groups. The WHO AWaRe classification was used to describe antibiotic use by the study participants and to assess the overlap in antibiotic use. Results: Our study provides evidence of an overlap in human and animal antibiotic use in rural community settings across the human and animal health sectors. Amoxicillin (access group), penicillin (access group), and ofloxacin (watch group) were used in both human and animal health. Amoxicillin and penicillin were used to treat common bacterial infections, ofloxacin was used to treat skin infections in humans and animals, and ofloxacin was used to treat pneumonia in animals and urinary bladder infections in humans. In contrast, azithromycin (watch group), cefixime (watch group), and amoxicillin (Access Group), with or without other antibiotics, were the most commonly used antibiotics by GPs in humans. Conclusion: We confirmed the overlap in antibiotic use across the human and animal health sectors in rural community settings, suggesting the need for interventions following the One Health approach. Further, research is required to assess the patterns of this overlap, as well as behavior, knowledge, and potential solutions to help avoid this overlap and prevent the rampant use of antibiotics in the animal and human health sectors in rural community settings. Keywords: antimicrobial resistance, antibiotics use, overlap, rural India, WHO AWaRe.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
International Journal of One Health
International Journal of One Health Veterinary-Veterinary (all)
CiteScore
2.10
自引率
0.00%
发文量
13
审稿时长
15 weeks
期刊介绍: International Journal of One Health publishes high quality and novelty papers focusing on One Health. Review articles are highly appreciated. All articles published by International Journal of One Health are made freely and permanently accessible online. All articles to International Journal of One Health are posted online immediately as they are ready for publication.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信