作为阿尔茨海默病生物标记物的α1-抗糜蛋白酶和其他炎症因子

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology Pub Date : 2023-12-07 DOI:10.21608/eajbsc.2023.328457

Haneen Alkaales, Shifaa Ibrahim

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引用次数: 0

摘要

从 AD 的病理学角度看，淀粉样蛋白积累后会导致神经元炎症和退化。这项研究的目的是研究注意力缺失症与参与者血液中一些蛋白质水平（如α1-抗糜蛋白酶、高敏感C反应蛋白和1 interlukin-6）之间的关系。参与本研究的患者中，有 130 人主诉患有注意力缺失症，他们根据年龄被分为两组，80 名正常人作为对照组。所有患者和正常人的血清均用于检测α-1-抗糜蛋白酶、高敏C反应蛋白和interlukin-6的水平。

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Alpha 1- Anti-chymotrypsin and Other Inflammatory Factors As Biomarkers for Alzheimer's Disease

pathology of AD reveals neuronal inflammation and degeneration following amyloid accumulation. The aim of this research is to study the relationship between AD & the level of some proteins like alpha1-anti chymotrypsin, high sensitive C-reactive protein and 1 interlukin-6 in the blood of participants. Patients, included in this study, are 130 one complaining of AD, they were divided into two groups according to their age. while 80 normal people are involved in this study as a control group. The serum of all patients and normal subjects were taken for detection of the level of alpha-1-anti chymotrypsin, high sensitive C-reactive protein and interlukin-6.

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Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

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