德拉马尼安全性和有效性分析

Q4 Medicine

Tuberculosis and Lung Diseases Pub Date : 2023-12-25 DOI:10.58838/2075-1230-2023-101-6-102-110

G. Mozhokina, A. Samoylova, I. A. Vasilyeva, A. Abramchenko

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引用次数: 0

摘要

这篇综述分析了50篇关于使用含有德拉马尼这种新药的治疗方案治疗多重耐药性结核病的文章。地拉米尼具有双重杀菌作用，不仅能抑制活性结核分枝杆菌，还能抑制休眠结核分枝杆菌。综述介绍了在综合化疗中使用德拉马尼的有效性和安全性的临床研究结果。综述展示了扩大使用德拉马尼治疗成人和儿童的前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Delamanid: Safety and Efficacy Analysis

The review presents the analysis of 50 publications describing treatment of multiple drug resistant tuberculosis with regimens containing the new drug of delamanid. Delamanid possesses a dual bactericidal effect not only against active but also dormant Mycobacterium tuberculosis. The results of clinical studies on the efficacy and safety of delamanid within comprehensive chemotherapy are presented. The review demonstrates prospects for expanding the use of delamanid for treatment of adults and children.

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来源期刊

Tuberculosis and Lung Diseases Medicine-Pulmonary and Respiratory Medicine

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

8 weeks

期刊介绍： The Journal is aimed for professional development of researchers, doctors, teachers of medical universities and training institutions. The Journal focuses on the presentation of results of research, case studies, issues of differential diagnostics and treatment in the phthisiologist’s practice, national programs on tuberculosis control in the Russian Federation, WHO strategies, discussion of prevention issues to stop transmission of TB/HIVco-infection, and extrapulmonary tuberculosis.